Results 141 to 150 of about 1,822,086 (171)

Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice

Journal of Hepatology, 2003
Mutations in genes encoding the ATP-binding cassette (ABC)-transporters ABCG5 and ABCG8 underlie sitosterolemia, which is characterized by elevated plasma levels of phytosterols due to increased intestinal absorption and impaired biliary secretion of sterols.
Kosters, Astrid, Frijters, Raoul J. J. M., Schaap, Frank G., Vink, Edwin, Plösch, Torsten, Ottenhoff, Roelof, Jirsa, Milan, de Cuyper, Iris M., Kuipers, Folkert, Groen, Albert K.   +9 more
openaire   +4 more sources

Inhibition of Ceramide Decreased the Expression of ATP-Binding Cassette Transporter G5/8 mRNA in an Animal Model of Cholesterol Gallstone

Digestive Diseases, 2017
<b><i>Background:</i></b> The increased risk of gallstone has been reported in patients with ATP-binding cassette (ABC) transporter polymorphism. The half-transporters ABCG5 and ABCG8 mediate the efflux of cholesterol in hepatocytes and the intestine.
Hyo Jung, Kim, Jae Seon, Kim, Seikwan, Oh, Hwan-Soo, Yoo   +3 more
openaire   +2 more sources

Scavenger Receptor Class B Type I Mediates Biliary Cholesterol Secretion Independent of ATP-Binding Cassette Transporter g5/g8 in Mice†

Hepatology, 2009
Scavenger receptor class B type I (SR-BI) mediates selective uptake of cholesterol from high-density lipoprotein (HDL) particles by the liver and influences biliary cholesterol secretion. However, it is not clear, if this effect is direct or indirect.
Wiersma, Harmen, Gatti, Alberto, Nijstad, Niels, Oude Elferink, Ronald P. J., Kuipers, Folkert, Tietge, Uwe J. F.   +5 more
openaire   +2 more sources

Lymphatic Absorption and Deposition of Various Plant Sterols in Stroke‐Prone Spontaneously Hypertensive Rats, a Strain Having a Mutation in ATP binding cassette transporter G5

Lipids, 2007
AbstractATP binding cassette transporter G5 (ABCG5) and ATP binding cassette transporter G8 (ABCG8) have been suggested to transport absorbed plant sterols and cholesterol from enterocytes to the intestinal lumen and from hepatocytes to bile. It has been thought that mutations of ABCG5 or ABCG8 cause the deposition of plant sterols in the body.
Tadateru, Hamada, Nami, Egashira, Shoko, Nishizono, Hiroko, Tomoyori, Hideaki, Nakagiri, Katsumi, Imaizumi, Ikuo, Ikeda   +6 more
openaire   +2 more sources

2P-0450 Identification of a novel mutation in the ATP-binding cassette transporter G5 (ABCG5) in a Japanese patient with sitosterolemia

Atherosclerosis Supplements, 2003
M. Koseki, A. Matsuyama, M. Ishigami, K. Hirano, N. Sakai, H. Hiraoka, T. Nakamura, H. Hattori, M. Nagano, T. Egashira, S. Yamashita, Y. Matsuzawa   +11 more
openaire   +1 more source

S1236 Inhibition of Ceramide Decreased the Expression of ATP-Binding Cassette Transporter G5 mRNA in the Animal Model of Cholesterol Gallstone

Gastroenterology, 2010
Hyo Jung Kim, Jae Seon Kim, Han Byul Chun, Su Rin Shin, Jin Bae Kim, Il Hyun Baek, Myung Seok Lee, Seikwan Oh, Youn-Sun Lee, Hwan-Soo Yoo   +9 more
openaire   +1 more source

Cyclosporine A Reduces ATP-Binding Cassette Transporter G5 (ABCG5) and G8 (ABCG8) Gene Expression and Protein in Caco-2 Cells

Journal of Clinical Lipidology, 2012
Matthew K. Ito, Shobana Ganesan, Grace I. Judd, Atanaz Zargar, Ali J. Olyaie   +4 more
openaire   +1 more source

LIVER X RECEPTOR-MEDIATED ACTIVATION OF MACROPHAGE-SPECIFIC REVERSE CHOLESTEROL TRANSPORT IN VIVO REQUIRES ATP-BINDING CASSETTE (ABC) G5/G8

Atherosclerosis Supplements, 2008
N. Rotllan, L. Calpe-Berdiel, C. Fievet, R. Roig, F. Blanco-Vaca, J.C. Escola-Gil   +5 more
openaire   +1 more source

Identification of ABCC5 Among ATP-Binding Cassette Transporter Family as a New Biomarker for Hepatocellular Carcinoma Based on Bioinformatics Analysis

International Journal of General Medicine, 2021
Jing Wu, Jing Wu, Jiaheng Xie
exaly