Results 81 to 90 of about 2,022 (165)
Regulation of biliary cholesterol secretion and reverse cholesterol transport [PDF]
According to the World Health Organization the number one cause of death throughout the world is cardiovascular disease. Therefore, there is an urgent need for new therapeutic strategies to prevent and treat cardiovascular disease. One possible way is to
Dikkers, Arne
core +2 more sources
REGULATION OF ABCG5 AND ABCG8 STEROL TRANSPORTERS IN BILIARY CHOLESTEROL ELIMINATION, REVERSE CHOLESTEROL TRANSPORT AND DYSLIPIDEMIA [PDF]
ATP-binding cassette transporters ABCA1 and ABCG1 initiate reverse cholesterol transport generating HDL particles, whereas ABCG5/G8 promote biliary cholesterol secretion thereby facilitating the last step of reverse cholesterol transport.
Sabeva, Nadezhda Steliyanova
core +1 more source
Affected by abundant PLTP : the atherogenic role of a lipid transfer protein in transgenic mice [PDF]
__Abstract__ Atherosclerosis is a progressive disease of the large and medium-sized arteries. The disease is characterised by endothelial dysfunction, inflammation and the accumulation of fatty and fibrous substances in the vessel wall, resulting in
Moerland, M. (Matthijs) +1 more
core
How active cholesterol coordinates cell cholesterol homeostasis: Test of a hypothesis [PDF]
How do cells coordinate the diverse elements that regulate their cholesterol homeostasis? Our model postulates that membrane cholesterol forms simple complexes with bilayer phospholipids.
Lange, Yvonne, Steck, Theodore L.
core +1 more source
Regulation of hepatobiliary transport function by nuclear receptors [PDF]
The work described in this thesis deals with the role of nuclear receptors in transcriptional control and function of transporters involved in the generation of bile. Bile formation is one of the major functions of the liver.
Kok, Tineke
core
ABC transzporterek genetikai polimorfizmusainak vizsgálata aszimmetrikus PCR-t követő olvadáspont analízis alkalmazásával [PDF]
Szilvási, Anikó
core +1 more source
Gut microbial composition and activity exert a strong influence on the metabolic phenotype of the host, and variation in the metabolic phenotype is a major factor underlying inter-individual variation in drug responses.
Swann, Jonathan Richard +1 more
core

