Results 81 to 90 of about 1,805,873 (166)
Structural Features of the ATP-Binding Cassette (ABC) Transporter ABCA3
In this review we reported and discussed the structural features of the ATP-Binding Cassette (ABC) transporter ABCA3 and how the use of bioinformatics tools could help researchers to obtain a reliable structural model of this important transporter.
Alessandro Paolini +3 more
core +1 more source
ATP-Binding Cassette Transporter of Clinical Significance: Sideroblastic Anemia [PDF]
The ATP-binding cassette (ABC) transporters are a vast group of 48 membrane proteins, some of which are of notable physiological and clinical importance.
Harris, Neil +11 more
core +1 more source
Vacuolar sequestration or cellular extrusion of glutathione-conjugated xenobiotics and catabolites by ATP-binding cassette (ABC) transporters is an important detoxification mechanism operating in many species.
Mamnun YM +6 more
core +1 more source
Characterisation of the vibrio cholerae antibiotic resistance var operon [PDF]
The discovery and use of antibiotics in the chemotherapy of bacterial infections has revolutionised medicine as it is today. Unfortunately, the progressive use of antibiotics has promoted the evolution of bacterial defences against these mediators and ...
Massam-Wu, Teresa
core
Snapshots of the maltose transporter during ATP hydrolysis
ATP-binding cassette transporters are powered by ATP, but the mechanism by which these transporters hydrolyze ATP is unclear. In this study, four crystal structures of the full-length wild-type maltose transporter, stabilized by adenosine 5′-
Michael L. Oldham, Jue Chen
core +1 more source
Strict coupling between CFTR's catalytic cycle and gating of its Cl- ion pore revealed by distributions of open channel burst durations [PDF]
CFTR, the ABC protein defective in cystic fibrosis, functions as an anion channel. Once phosphorylated by protein kinase A, a CFTR channel is opened and closed by events at its two cytosolic nucleotide binding domains (NBDs).
Gadsby, DC, Csanady, L, Vergani, P
core
Increased LDL-C reduction with ezetimibe in ketogenic diet-induced hypercholesterolemia. [PDF]
Gonzalez J +6 more
europepmc +1 more source

