Diabetes/Metabolism Research and Reviews, Volume 40, Issue 2, February 2024.Abstract Aims Type 2 Diabetes is intrinsically linked to cardiovascular disease (CVD) via diabetic dyslipidemia, both of which remain global health concerns with annually increasing prevalence. Given the established links between gut microbiome dysbiosis and metabolic diseases, its modulation is an attractive target to ameliorate metabolic imbalances ...
Ridhima Kaul +4 more
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Redox Experimental MedicineObjective: We tested the effect of 27-hydroxycholesterol (27OHC) on the expression and synthesis of two membrane transporters involved in sterols extrusion from the intestinal epithelium into the gut lumen: ATP-binding cassette A1 (ABCA1) and G8 (ABCG8).
Noemi Iaia +3 more
doaj +1 more source
Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice [PDF]
, 2020 Active secretion of bile salts into the canalicular lumen drives bile formation and promotes biliary cholesterol and phospholipid output. Disrupting hepatic bile salt uptake, by inhibition of sodium-taurocholate cotransporting polypetide (NTCP; Slc10a1 ...
Donkers, Joanne M +10 more
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Adaptive capabilities and fitness consequences associated with pollution exposure in fish [PDF]
, 2016 Many fish populations are exposed to harmful levels of chemical pollution and selection pressures associated with these exposures have led to the evolution of tolerance.
Hamilton, Patrick +3 more
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Pharmacogenomics in cardiovascular disorders: Steps in approaching personalized medicine in cardiovascular medicine [PDF]
, 2009 Christopher Barone, Shaymaa S Mousa, Shaker A MousaThe Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, Albany, NY, USAAbstract: Some of the most commonly prescribed medications are those for cardiovascular maladies. The
Christopher Barone +2 more
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Studies on PCSK9 in the regulation of cholesterol metabolism [PDF]
, 2011 Elevated levels of plasma cholesterol, mainly in low density lipoproteins (LDL), are a major risk factor for coronary heart disease. The level of plasma LDL cholesterol (LDL-C) is largely dependent on the number of hepatic LDL receptors (LDLRs ...
Persson, Lena
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Mennyiségi molekuláris genetikai vizsgálatok és nagy kapacitású sejtelválasztás együttes alkalmazása rosszindulatú myeloid megbetegedéskeben = Combined application of molecular genetic techniques and high capacity cell sorting in malignant myeloid diseases [PDF]
, 2012 Többféle molekuláris diagnosztikai módszer alkalmazásával vizsgáltuk új örökletes tényezők hatását a kórképek kialakulására és klinikai sajátosságaira rosszindulatú myeloid megbetegedésekben.
Andrikovics, Hajnalka +4 more
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Intestinal absorption, hepatic synthesis, and biliary secretion of cholesterol: Where are we for cholesterol gallstone formation? [PDF]
, 2012 With a 10%-15% prevalence, gallstone disease is one of the most prevalent and costly digestive diseases in Western countries. About two-thirds of gallstones are cholesterol gallstones, while the remaining are pigment stones that contain less than 30 ...
PORTINCASA, Piero, Wang DQH
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Enhanced bioavailability of zeaxanthin in a milk-based formulation of wolfberry (Gou Qi Zi;Fructus barbarum L.) [PDF]
, 2017 The carotenoid zeaxanthin is concentrated within the macula. Increased macular zeaxanthin is suggested to lower the risk of age-related macular degeneration.
Benzie, Iris F. F. +4 more
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UEG Week 2025 Moderated Posters
United European Gastroenterology Journal, Volume 13, Issue S8, Page S189-S802, October 2025.
wiley +1 more source