Results 51 to 60 of about 1,805,873 (166)

Fingerprint of the mitochondrial ABC transporter Mdl1p from Saccharomyces cerevisiae [PDF]

, 2006
The multidrug resistance like protein 1 (Mdl1p) belongs to the class of ATP binding cassette (ABC) transporters which comprise a large family of membrane proteins utilising ATP hydrolysis to drive up-hill transport of a wide variety of solutes across ...
Hofacker, Matthias
core  

MOESM7 of Structural and functional insights into the Diabrotica virgifera virgifera ATP-binding cassette transporter gene family

, 2019
Additional file 7.
Folukemi Adedipe (3508040), Marcé Lorenzen (8056631), Brian Wiegmman (8056628), Brad Coates (575729), Nathaniel Grubbs (397043)   +4 more
core   +1 more source

Conformational changes in the catalytically inactive nucleotide-binding site of CFTR. [PDF]

, 2013
A central step in the gating of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is the association of its two cytosolic nucleotide-binding domains (NBDs) into a head-to-tail dimer, with two nucleotides bound at the ...
Mihályi Csaba, Vergani P, Töröcsik, B, Csanády, László, Csanády László, Mihályi, C, Csaba Mihályi, Paola Vergani, Vergani, Paola, Beáta Töröcsik, Szollosi, A, László Csanády, Szőllősi, András, Szöllősi András, Törőcsik, Beáta, Mihályi, Csaba, Andras Szollosi, Vergani, P, Törőcsik Beáta, Csanády, L   +19 more
core   +1 more source

Oat β‐Glucan and Galactooligosaccharides Influence Gallstone Formation by Modulating the Gut Microbiota, Particularly Desulfovibrionales

iMetaMed, Volume 2, Issue 1, March 2026.
Oat β‐glucan and galactooligosaccharides influence the formation of gallstones by modulating the gut microbiota, particularly the abundance of Desulfovibrionales. The primary mechanism involves metabolic byproducts associated with Desulfovibrionales inhibiting hepatic bile acid synthesis via both the hepatic FXR–SHP and intestinal FXR–FGF15 signaling ...
Liang Tian, Yanyan Lin, Ping Yue, Long Gao, Leiqing Wang, Chongfei Huang, Jinyu Zhao, Ningzu Jiang, Jiahui xi, Haidong Ma, Zhen Liu, Ruyang Zhong, Wenkang Fu, Ningning Mi, Mingzhen Bai, Bodong Zhang, Lunzhi Dai, Jiang Li, Hu Chen, Jinqiu Yuan, Wenbo Meng   +20 more
wiley   +1 more source

Mechanistic insights into ATP hydrolysis by the ABC transporter TAP [PDF]

, 2004
The transporter associated with antigen processing (TAP) plays a pivotal role in the adaptive immune response against virus-infected or malignantly transformed cells.
Chen, Min
core  

Inhibition of Intestinal Cholesterol Absorption by Ocimum sanctum L. Flower Aqueous Extract via Changing Physicochemical Properties of Cholesterol Micelles

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Hyperlipidemia is recognized as a major contributor to chronic noncommunicable diseases. The primary strategy regarding hyperlipidemia prevention is involved in the blockade of intestinal cholesterol absorption. Ezetimibe (Eze) is the sole prescribed drug that targets Niemann‐Pick C1 Like 1 (NPC1L1), a key cholesterol transporter, resulting in reduced ...
Jakkapong Inchai, Atcharaporn Ontawong, Kongkiat Trisuwan, Kornwalai Tunkaew, Pannita Holasut, Thanthakan Saithong, Thippawan Yasanga, Chutima S. Vaddhanaphuti, Anupama Bose   +8 more
wiley   +1 more source

A new tool for engineering Phaeodactylum tricornutum: the METE promoter drives both high expression and B12‐tuneable regulation of transgenes

The Plant Journal, Volume 124, Issue 2, October 2025.
Significance Statement The promoter of the METE gene in the diatom Phaeodactylum tricornutum is repressed by nanomolar concentrations of vitamin B12. It can be used to tune the expression of genes for reporter proteins or metabolic enzymes and in the non‐permissive state (i.e., +B12) can suppress the expression of the lethal gene, barnase.
Patrick R. Hickland, Katrin Geisler, Shelby Newsad, Marcel Llavero Pasquina, A. Caroline Faessler, Gonzalo I. Mendoza‐Ochoa, Andre Holzer, Payam Mehrshahi, Alison G. Smith   +8 more
wiley   +1 more source

Polymorphisms of the ATP-binding cassette sterol efflux transporter genes g5 and g8 in cardiovascular diseases and type 2 diabetes mellitus

Ateroscleroz
Mutations with a decrease in the expression and function of the of the ATP-binding cassette genes proteins ABCG5 and ABCG8, as the main sterol efflux transporters, lead to the accumulation of xenosterols in plasma associated with changes in the lipid profile, hyperglycemia and the risk of cardiovascular diseases (CVD) and type 2 diabetes mellitus (DM2).
I. N. Grigor’eva, T. E. Notova, T. S. Suvorova, D. L. Nepomnyashchikh   +3 more
openaire   +1 more source

Patients with symptoms of haemolytic anaemia and thrombocytopenia revealed by genetic testing as sitosterolemia

Clinical and Translational Discovery, Volume 5, Issue 4, August 2025.
For patients with unexplained haemolytic anaemia, thrombocytopenia, especially with stomatocytes present in peripheral blood, the diagnosis of sitosterolemia should be considered, and genetic testing is strongly recommended . Abstract Background Sitosterolemia is a rare, inherited, autosomal recessive disorder of lipid metabolism.
Mengjia Qian, Pu Chen, Yanxia Zhan, Bijun Zhu, Lingyan Wang, Miaomiao Zhang, Yujie Zhou, Hao Chen, Lili Ji, Yunfeng Cheng   +9 more
wiley   +1 more source

ABC transporters in Dictyostelium discoideum development [PDF]

, 2013
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins.
Adam Kuspa, Gad Shaulsky (10030), Toplak Marko, Balaji Santhanam, Zhuchenko Olga, Adam Kuspa (45348), Marko Toplak, Gad Shaulsky, Shaulsky, Gad, Miranda Edward Roshan, Balaji Santhanam (155206), Zupan Blaz, Santhanam, Balaji, Kuspa Adam, Zupan, Blaz, Edward Roshan Miranda (446004), Marko Toplak (446006), Zhuchenko, Olga, Edward Roshan Miranda, Blaz Zupan (10031), Miranda, Edward Roshan, Olga Zhuchenko, Kuspa, Adam, Blaz Zupan, Olga Zhuchenko (446005), Santhanam Balaji, Shaulsky Gad, Toplak, Marko   +27 more
core   +2 more sources