Results 111 to 120 of about 30,215 (258)
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
The dilemma for lipid productivity in green microalgae: importance of substrate provision in improving oil yield without sacrificing growth [PDF]
, 2016 10.1186/s13068-016-0671-2Biotechnology for Biofuels911 ...
Lee, Yuan Kun, Tan, Kenneth Wei Min
core +1 more source
Plant Direct, Volume 10, Issue 2, February 2026.ABSTRACT Arabidopsis thaliana gene At2g44130 encodes a Kelch‐like domain F‐box protein designated KFB39 and was previously shown to be specifically expressed on exposure to the oxylipin cis‐jasmone. In order to better understand the regulation of At2g44130, a forward genetic screen was carried out to identify mutants in which a promoter‐GUS fusion was ...
Michaela C. Matthes +3 more
wiley +1 more source
Nature Communications, 2019 Caspases are most closely associated with cell death, but many have other cellular functions. Here, Das et al. find that upon metabolic stress, caspase-10 cleaves ACLY to regulate metabolic homeostasis and epigenetic reprogramming by altering Acetyl-CoA ...
Rajni Kumari +2 more
doaj +1 more source
Toxins, 2013 The correlation of ATP citrate lyase (ACL) and acetyl CoA levels with trichothecene production in Fusarium graminearum was investigated using an inhibitor (precocene II) and an enhancer (cobalt chloride) of trichothecene production by changing carbon ...
Naoko Sakamoto +6 more
doaj +1 more source
Comparative biochemistry of CO2 fixation and the evolution of autotrophy [PDF]
, 2010 Carbon dioxide fixation is a polyphyletic trait that has evolved in widely separated prokaryotic branches. The three principal CO2-assimilation pathways are (i) the reductive pentose-phosphate cycle, i. e.
Ana María Velasco +3 more
core +2 more sources
Metabolic network analysis reveals microbial community interactions in anammox granules. [PDF]
, 2017 Microbial communities mediating anaerobic ammonium oxidation (anammox) represent one of the most energy-efficient environmental biotechnologies for nitrogen removal from wastewater.
Bhattacharjee, Ananda S +6 more
core +2 more sources
ATP‐citrate lyase from rat liver [PDF]
European Journal of Biochemistry, 1991 The mechanism of ATP‐citrate lyase has been proposed to involve a citryl‐enzyme intermediate. When the enzyme is incubated with its substrates ATP and [14C]citrate, but in the absence of the final acceptor, two distinct types of citrate‐containing complex can be isolated. At early time points, a highly unstable complex can be isolated by gel filtration
openaire +2 more sources
Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.This work presents the physiological exploration of the halo‐alkaliphilic, carboxydotrophic acetogen bacterium MD4. In contrast to well‐characterised neutrophilic and slightly acidophilic acetogenic carboxydotrophs, this work shows an important role for formate production, instead of ethanol, as a redox exhaust mechanism in alkaline conditions ...
Martijn Diender +5 more
wiley +1 more source
Genetics Selection Evolution, 2008 ATP-citrate lyase (ACL), one of the lipogenic enzymes, catalyses the formation of acetyl-coenzyme A (CoA) involved in the synthesis of fatty acid and cholesterol. In pig, very little is known about the ACL gene.
Xiong Yuan-Zhua +11 more
doaj +1 more source