Results 31 to 40 of about 331,724 (261)
Exocytotic Release of ATP from Cultured Astrocytes [PDF]
Journal of Biological Chemistry, 2007 Astrocytes appear to communicate with each other as well as with neurons via ATP. However, the mechanisms of ATP release are controversial. To explore whether stimuli that increase [Ca(2+)](i) also trigger vesicular ATP release from astrocytes, we labeled ATP-containing vesicles with the fluorescent dye quinacrine, which exhibited a significant co ...
PANGRSIC T +9 more
openaire +4 more sources
New platelet functional method for identification of pathogenic antibodies in HIT patients
Platelets, 2017 Heparin-induced thrombocytopenia (HIT) is a thrombotic complication of heparin therapy. The most used functional method for HIT diagnosis is serotonin release assay (SRA).
M. L. Guarino +6 more
doaj +1 more source
Storage and Release of ATP from Astrocytes in Culture [PDF]
Journal of Biological Chemistry, 2003 ATP is released from astrocytes and is involved in the propagation of calcium waves among them. Neuronal ATP secretion is quantal and calcium-dependent, but it has been suggested that ATP release from astrocytes may not be vesicular. Here we report that, besides the described basal ATP release facilitated by exposure to calcium-free medium, astrocytes ...
Coco S +7 more
openaire +5 more sources
Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats
Molecular Pain, 2008 Background Adenosine 5'-triphosphate (ATP) has a ubiquitous role in metabolism and a major role in pain responses after tissue injury. We investigated the changes in basal and KCl-evoked ATP release from rat dorsal root ganglia (DRG) after peripheral ...
Omoto Kevin S +8 more
doaj +1 more source
ATP Release from Human Airway Epithelial Cells Exposed to Staphylococcus aureus Alpha-Toxin
Toxins, 2016 Airway epithelial cells reduce cytosolic ATP content in response to treatment with S. aureus alpha-toxin (hemolysin A, Hla). This study was undertaken to investigate whether this is due to attenuated ATP generation or to release of ATP from the cytosol ...
Romina Baaske +6 more
doaj +1 more source
CO2-Induced ATP-Dependent Release of Acetylcholine on the Ventral Surface of the Medulla Oblongata. [PDF]
PLoS ONE, 2016 Complex mechanisms that detect changes in brainstem parenchymal PCO2/[H+] and trigger adaptive changes in lung ventilation are responsible for central respiratory CO2 chemosensitivity.
Robert T R Huckstepp +2 more
doaj +1 more source
Diacylglycerol Signaling Underlies Astrocytic ATP Release
Neural Plasticity, 2011 Astrocytes have the ability to modulate neuronal excitability and synaptic transmission by the release of gliotransmitters. The importance of ATP released downstream of the activation of Gq-coupled receptors has been well established, but the mechanisms ...
Alison E. Mungenast
doaj +1 more source
PLoS ONE, 2014 Urothelial cells respond to bladder distension with ATP release, and ATP signaling within the bladder and from the bladder to the CNS is essential for proper bladder function.
Hiromitsu Negoro +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan +1 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier +10 more
wiley +1 more source