Results 21 to 30 of about 331,724 (261)
eLife, 2018 Bone cells sense and actively adapt to physical perturbations to prevent critical damage. ATP release is among the earliest cellular responses to mechanical stimulation.
Nicholas Mikolajewicz +3 more
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Circadian Regulation of ATP Release in Astrocytes [PDF]
Journal of Neuroscience, 2011 Circadian clocks sustain daily oscillations in gene expression, physiology, and behavior, relying on transcription-translation feedback loops of clock genes for rhythm generation. Cultured astrocytes display daily oscillations of extracellular ATP, suggesting that ATP release is a circadian output. We hypothesized that the circadian clock modulates ATP
Luciano, Marpegan +8 more
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Mechanisms of constitutive and ATP-evoked ATP release in neonatal mouse olfactory epithelium
BMC Neuroscience, 2012 Background ATP is an extracellular signaling molecule with many ascribed functions in sensory systems, including the olfactory epithelium. The mechanism(s) by which ATP is released in the olfactory epithelium has not been investigated.
Hayoz Sébastien, Jia Cuihong, Hegg CC
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Journal of Pharmacological Sciences, 2007 ATP has broad functions as an autocrine/paracrine molecule. The mode of ATP release and its intracellular source, however, are little understood. Here we show that bradykinin via B2-receptor stimulation induces the extracellular release of ATP via the ...
Yumei Zhao +5 more
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ATP release via anion channels [PDF]
Purinergic Signalling, 2005 ATP serves not only as an energy source for all cell types but as an 'extracellular messenger' for autocrine and paracrine signalling. It is released from the cell via several different purinergic signal efflux pathways. ATP and its Mg(2+) and/or H(+) salts exist in anionic forms at physiological pH and may exit cells via some anion channel if the pore
Sabirov, Ravshan Z., Okada, Yasunobu
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A computational model of a microfluidic device to measure the dynamics of oxygen-dependent ATP release from erythrocytes. [PDF]
PLoS ONE, 2013 Erythrocytes are proposed to be involved in blood flow regulation through both shear- and oxygen-dependent mechanisms for the release of adenosine triphosphate (ATP), a potent vasodilator.
Richard J Sove +3 more
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Sphingosine-1-Phosphate Induces ATP Release via Volume-Regulated Anion Channels in Breast Cell Lines
Life, 2021 High interstitial level of ATP and its lysate adenosine in the cancer microenvironment are considered a halo mark of cancer. Adenosine acts as a strong immune suppressor. However, the source of ATP release is unclear.
Kishio Furuya +3 more
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Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner
Journal of Lipid Research, 2006 Sphingosine 1-phosphate (S1P) is accumulated in platelets and released on stimulation by thrombin or Ca2+. Thrombin-stimulated S1P release was inhibited by staurosporin, whereas Ca2+-stimulated release was not.
Nobuyoshi Kobayashi +6 more
doaj +1 more source
Purinergic responses of chondrogenic stem cells to dynamic loading [PDF]
Journal of the Serbian Chemical Society, 2013 In habitually loaded tissues, dynamic loading can trigger ATP (adenosine 5’- triphosphate) release to extracellular environment, and result in calcium signaling via ATP binding to purine P2 receptors1.
Gađanski Ivana +1 more
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Renal epithelial cells can release ATP by vesicular fusion
Frontiers in Physiology, 2013 Renal epithelial cells have the ability to release nucleotides as paracrine factors. In the intercalated cells of the collecting duct, ATP is released by connexin30 (cx30), which is selectively expressed in this cell type.
Randi G Bjaelde +4 more
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