Ingredients of Vicks VapoRub inhibit rhinovirus-induced ATP release [PDF]
Drugs in Context, 2023 Background: Over-the-counter therapies, such as Vicks VapoRub, are frequently used in the management of upper respiratory tract infection symptoms.
Rebecca J Stinson +3 more
doaj +2 more sources
Mathematical model for promotion of wound closure with ATP release [PDF]
Biophysics and Physicobiology, 2023 To computationally investigate the recent experimental finding such that extracellular ATP release caused by exogeneous mechanical forces promote wound closure, we introduce a mathematical model, the Cellular Potts Model (CPM), which is a popular ...
Kenta Odagiri +3 more
doaj +2 more sources
Hypoxia induces robust ATP release from erythrocytes in ApoE-LDLR double-deficient mice [PDF]
Frontiers in PhysiologyRed blood cells (RBCs) play a role in the regulation of vascular tone via release of adenosine triphosphate (ATP) into the vasculature in response to various stimuli.
Fatih Celal Alcicek +8 more
doaj +2 more sources
ATP release mediated by TRPM3 enhances invasion in glioblastoma [PDF]
Animal Cells and SystemsGlioblastoma (GBM) is the most aggressive and lethal form of primary brain tumor, characterized by uncontrolled proliferation and invasion into surrounding brain tissue.
Kkot Garam Bae +11 more
doaj +2 more sources
TRPV2 modulates mechanically Induced ATP Release from Human bronchial epithelial cells [PDF]
Respiratory ResearchRepetitive bouts of coughing expose the large airways to significant cycles of shear stress. This leads to the release of alarmins and the tussive agent adenosine triphosphate (ATP) which may be modulated by the activity of ion channels present in the ...
Orla M. Dunne +7 more
doaj +2 more sources
cAMP/protein kinase A activates cystic fibrosis transmembrane conductance regulator for ATP release from rat skeletal muscle during low pH or contractions. [PDF]
PLoS ONE, 2012 We have shown that cystic fibrosis transmembrane conductance regulator (CFTR) is involved in ATP release from skeletal muscle at low pH. These experiments investigate the signal transduction mechanism linking pH depression to CFTR activation and ATP ...
Jie Tu +3 more
doaj +1 more source
Air-stimulated ATP release from keratinocytes occurs through connexin hemichannels. [PDF]
PLoS ONE, 2013 Cutaneous ATP release plays an important role in both epidermal stratification and chronic pain, but little is known about ATP release mechanisms in keratinocytes that comprise the epidermis.
Travis P Barr +5 more
doaj +1 more source
Metabolites, 2022 Adenosine 5′-triphosphate (ATP) is released in the bladder lumen during filling. Urothelial ATP is presumed to regulate bladder excitability. Urinary ATP is suggested as a urinary biomarker of bladder dysfunctions since ATP is increased in the urine of ...
Alejandro Gutierrez Cruz +4 more
doaj +1 more source
ATP release from vascular endothelia occurs across Cx43 hemichannels and is attenuated during hypoxia. [PDF]
PLoS ONE, 2008 Extracellular ATP is an important signaling molecule for vascular adaptation to limited oxygen availability (hypoxia). Here, we pursued the contribution of vascular endothelia to extracellular ATP release under hypoxic conditions.We gained first insight ...
Marion Faigle +4 more
doaj +1 more source
Lytic Release of Cellular ATP: Physiological Relevance and Therapeutic Applications
Life, 2021 The lytic release of ATP due to cell and tissue injury constitutes an important source of extracellular nucleotides and may have physiological and pathophysiological roles by triggering purinergic signalling pathways.
Ryszard Grygorczyk +7 more
doaj +1 more source