Results 91 to 100 of about 837,065 (393)
The Role of Mitochondrial H+-ATP Synthase in Cancer
Frontiers in Oncology, 2018 Cancer cells reprogram energy metabolism by boosting aerobic glycolysis as a main pathway for the provision of metabolic energy and of precursors for anabolic purposes. Accordingly, the relative expression of the catalytic subunit of the mitochondrial H+-
Pau B. Esparza-Moltó, José M. Cuezva
doaj +1 more source
Highly divergent mitochondrial ATP synthase complexes in Tetrahymena thermophila. [PDF]
PLoS Biology, 2010 The F-type ATP synthase complex is a rotary nano-motor driven by proton motive force to synthesize ATP. Its F(1) sector catalyzes ATP synthesis, whereas the F(o) sector conducts the protons and provides a stator for the rotary action of the complex ...
Praveen Balabaskaran Nina +6 more
doaj +1 more source
Cells, 2023 The mitochondrial permeability transition pore (mPTP) is a large, weakly selective pore that opens in the mitochondrial inner membrane in response to the pathological increase in matrix Ca2+ concentration.
Maria A. Neginskaya +2 more
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ATP synthase and Alzheimer’s disease: putting a spin on the mitochondrial hypothesis
Aging, 2020 It is estimated that over 44 million people across the globe have dementia, and half of these cases are believed to be Alzheimer’s disease (AD).
Brad Ebanks +2 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Structure, mechanism, and regulation of the chloroplast ATP synthase
Science, 2018 Protons find a path Adenosine triphosphate (ATP) synthases are dynamos that interconvert rotational and chemical energy. Capturing the complete structure of these multisubunit membrane-bound complexes has been hindered by their inherent ability to adopt ...
Alexander Hahn +4 more
semanticscholar +1 more source
A Therapeutic Role for the F1FO-ATP Synthase [PDF]
SLAS Discovery, 2019 Recently, the F1FO-ATP synthase, due to its dual role of life enzyme as main adenosine triphosphate (ATP) maker and of death enzyme, as ATP dissipator and putative structural component of the mitochondrial permeability transition pore (mPTP), which triggers cell death, has been increasingly considered as a drug target.
Nesci S. +3 more
openaire +3 more sources
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
FEBS Letters, EarlyView.Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase [PDF]
, 2016 Misfolded α-synuclein is a key factor in the pathogenesis of Parkinson's disease (PD). However, knowledge about a physiological role for the native, unfolded α-synuclein is limited.
Abramov, A +5 more
core
, 2012 Thermophilic enzymes can operate at higher temperatures but show reduced activities at room temperature. They are in general more stable during preparation and, accordingly, are considered to be more rigid in structure.
Boersch, Michael +7 more
core +1 more source