Results 171 to 180 of about 329,086 (345)

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Rotation-direction-dependent regulation of ATPase inhibitory factor 1 for mitochondrial ATP synthase from atomistic simulation [PDF]

Ryohei Kobayashi, Kei-ichi Okazaki
openalex   +1 more source

ATP Synthase Subunit Epsilon Overexpression Promotes Metastasis by Modulating AMPK Signaling to Induce Epithelial-to-Mesenchymal Transition and Is a Poor Prognostic Marker in Colorectal Cancer Patients [PDF]

, 2019
Yan‐Jiun Huang, Yi‐Hua Jan, Yu‐Chan Chang, Hsing‐Fang Tsai, Alexander T.H. Wu, Chi‐Long Chen, Michael Hsiao   +6 more
openalex   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source

Endothelial cell surface F ₁ -F _O ATP synthase is active in ATP synthesis and is inhibited by angiostatin

, 2001
Tammy L. Moser, Daniel J. Kenan, Timothy A. Ashley, Julie A. Roy, Michael D. Goodman, Uma Kant Misra, Dennis J. Cheek, Salvatore V. Pizzo   +7 more
openalex   +1 more source

Quantitative Determination of Direct Binding of b Subunit to F1 in Escherichia coli F1F0-ATP Synthase [PDF]

, 2004
Joachim Weber, Susan Wilke-Mounts, Sashi Nadanaciva, Alan E. Senior   +3 more
openalex   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

An atlas of mitochondrial ATP synthase activity across the lifespan. [PDF]

Mol Metab
Saqib M, Sarver DC, Nguyen CM, Chen F, Seldin MM, Wong GW.   +5 more
europepmc   +1 more source

High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane

, 2018
Anurag P. Srivastava, Min Luo, Wenchang Zhou, J. Symerský, Dongyang Bai, Melissa G. Chambers, José D. Faraldo‐Gómez, Maofu Liao, David M. Mueller   +8 more
openalex   +2 more sources

2,8‐Diazido‐ATP — a short‐length bifunctional photoaffinity label for photoaffinity cross‐linking of a stable F₁ in ATP synthase (from thermophilic bacteria PS3) [PDF]

, 1995
Hans‐Jochen Schäfer, Gabriele Rathgeber, Y Kagawa   +2 more
openalex   +1 more source