Results 251 to 260 of about 837,065 (393)
Src Reduces Neutrophil Extracellular Traps Generation and Resolves Acute Organ Damage
Src reduces neutrophil extracellular traps (NETs) generation and resolves acute organ damage. Src directly activates RAF1 by regulating phosphorylation at the Ser 621 site and mediates the RAF/MEK/ERK pathway, thereby affecting the intracellular ROS production. Alternatively, Src activates the RAF1/MEK/ERK pathway by mediating PKC phosphorylation.
Guotao Lu +18 more
wiley +1 more source
The molecular mechanism of ATP synthase constrains the evolutionary landscape of chemiosmosis. [PDF]
Macdonald JE, Ashby PD.
europepmc +1 more source
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan +10 more
wiley +1 more source
Ametryn and Clomazone Disrupt Mitochondrial Bioenergetics in Rat Liver: Evidence for Inhibition of Complexes I and II and ATP Synthase. [PDF]
Dos Santos Silva HP +5 more
europepmc +1 more source
Characterization of a b2δ Complex fromEscherichia coli ATP Synthase [PDF]
Stanley D. Dunn, Jennifer Chandler
openalex +1 more source
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun +16 more
wiley +1 more source
Energy Coupling, Turnover, and Stability of the F0F1 ATP Synthase Are Dependent on the Energy of Interaction between γ and β Subunits [PDF]
Marwan K. Al‐Shawi +2 more
openalex +1 more source
Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal +15 more
wiley +1 more source

