Results 271 to 280 of about 329,086 (345)

Breaking the energy chain: importance of ATP synthase in <i>Mycobacterium tuberculosis</i> and its potential as a drug target. [PDF]

RSC Med Chem
Perveen S, Pal S, Sharma R.
europepmc   +1 more source

An NADH-controlled gatekeeper of ATP synthase

Fabian Schildhauer, Petra S. J. Ryl, Simon Lauer, Swantje Lenz, Ayşe Berçin Barlas, Vasileios R. Ouzounidis, Kate L. Jeffrey, Daniel-Cosmin Marcu, Francis J. O’Reilly, Andrea Graziadei, Marchel Stuiver, Kita Schmidt, Helge Ewers, C.M.T. Spahn, Ezgi Karaca, Karl Emanuel Busch, Dhanya K. Cheerambathur, David Schwefel, Juri Rappsilber   +18 more
openalex   +1 more source

Switch of ATP synthase

Seibutsu Butsuri, 2001
openaire   +2 more sources

F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway

Advanced Science, EarlyView.
In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu, Meiching Ong, Xuewen Yi, Muqiong Xing, Xinyao Tian, Ke Zhang, Ling Lu, Hao Wang, Xiaohan Lin, Jun Fang, Aibo Mu, Jiaying Cao, Jingyu Jiang, Feng Gao, Hongjun Li, Baohong Wang, Qi Ling   +16 more
wiley   +1 more source

Correction to "Defective Dimerization of FoF1-ATP Synthase Secondary to Glycation Favors Mitochondrial Energy Deficiency in Cardiomyocytes During Aging". [PDF]

Aging Cell
europepmc   +1 more source

The landscape of rare mitochondrial DNA variants in sudden cardiac death: A potential role for ATP synthase. [PDF]

Heliyon
Luppi E, De Luise M, Bini C, Pelletti G, Tioli G, Kurelac I, Iommarini L, Pelotti S, Gasparre G.   +8 more
europepmc   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Variability of Clinical Phenotypes Caused by Isolated Defects of Mitochondrial ATP Synthase. [PDF]

Physiol Res
Tauchmannová K, Pecinová A, Houštěk J, Mráček T.   +3 more
europepmc   +1 more source

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

Advanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao, Jiahe Su, Jiawei Yuan, Qinyan Cao, Yue Wu, Yuyang Xiao, Guang Yang, Ruomu Xia, Jingpeng Yang, Yanan Li, Lina Wu, He Huang, Lingtong Meng   +12 more
wiley   +1 more source

N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase. [PDF]

Commun Biol
Coluccino G, Negro A, Filippi A, Bean C, Muraca VP, Gissi C, Canetti D, Mimmi MC, Zamprogno E, Ciscato F, Acquasaliente L, De Filippis V, Comelli M, Carraro M, Rasola A, Gerle C, Bernardi P, Corazza A, Lippe G.   +18 more
europepmc   +1 more source