Results 311 to 320 of about 837,065 (393)
This study establishes a bio‐electroceutical interface by synergizing engineered exosome‐derived biological signals with electroconductive microneedle‐delivered electrical cues, achieving dual‐pathway reprogramming of the diabetic neurovascular niches and accelerating wound healing. Abstract Diabetic wound healing remains a major clinical challenge due
Di Liu +5 more
wiley +1 more source
Correction to "Defective Dimerization of FoF1-ATP Synthase Secondary to Glycation Favors Mitochondrial Energy Deficiency in Cardiomyocytes During Aging". [PDF]
europepmc +1 more source
Variability of Clinical Phenotypes Caused by Isolated Defects of Mitochondrial ATP Synthase. [PDF]
Tauchmannová K +3 more
europepmc +1 more source
This study engineers Yarrowia lipolytica to produce succinic acid (SA) from lignocellulosic biomass. Adaptive evolution and multi‐omics analysis identify regulators that alleviate xylose metabolic disorder. Multi‐copy integration of xylose metabolic genes resolves redox imbalances from a futile fatty acid cycle, producing high‐titer SA from corn stover
Yutao Zhong +7 more
wiley +1 more source
N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase. [PDF]
Coluccino G +18 more
europepmc +1 more source
Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation
A peptide that replicates the amino acid sequence in Insig1/2 loop 1 inhibits the IGF1‐induced interaction between PCK1 and Insig1/2, PCK1‐mediated phosphorylation of Insig1/2, and SREBP activity‐dependent lipid synthesis. Administration of the LNP‐Insig1/2 loop 1 peptide effectively attenuates tumor growth and sensitizes tumors to the antitumor effect
Shudi Luo +10 more
wiley +1 more source
Inhibition of the ATP synthase c subunit ameliorates HDM/LPS-induced inflammatory responses in asthmatic bronchial epithelial cells by blocking the mPTP-mtDNA-cGAS-STING axis. [PDF]
Wang D +7 more
europepmc +1 more source
The CtrCBL1‐CtrCIPK6 module of trifoliate orange (Citrus trifoliata L.) phosphorylates CtrBBX32, triggering its protein degradation under cold conditions, thereby relieving CtrBBX32‐mediated transcriptional repression of CtrZAT10 and CtrSTP1. The consequent upregulation of CtrZAT10 further activates CtrSTP1 expression, which enhances hexose transport ...
Xiangming Shang +10 more
wiley +1 more source

