Results 71 to 80 of about 165,086 (247)

Synergistic Combination of Tamoxifen–Tetraphenylethylene Co‐Assembled Micelles and Orlistat‐Induced Lipid Droplet Inhibition to Overcome Tamoxifen Resistance

open access: yesAdvanced Healthcare Materials, EarlyView.
Molecule 2, which contains a shorter oligoether chain, binds to tamoxifen via structural similarity forming micelles with a positive surface charge, thereby enhancing cellular uptake. These fluorescent micelles induce lipid droplet (LD) accumulation, exhibit strong fluorescence, and effectively overcome tamoxifen resistance by synergizing with orlistat‐
Jung Yeon Park   +4 more
wiley   +1 more source

Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP

open access: yeseLife, 2019
ATP synthase produces the majority of cellular energy in most cells. We have previously reported cryo-EM maps of autoinhibited E. coli ATP synthase imaged without addition of nucleotide (Sobti et al.
Meghna Sobti   +9 more
doaj   +1 more source

Geometrically Controlled WNT Activation Drives Intestinal Morphogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Crypt‐villi‐like morphogenesis can be driven and controlled via architectural patterns in colorectal cells with the use of digital light processing printing. The resulting mini tissues exhibit budding structures and functionality, as evidenced by increased mucin expression.
Nathaniel C. Burmas   +3 more
wiley   +1 more source

Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM

open access: yeseLife, 2015
Adenosine triphosphate (ATP), the chemical energy currency of biology, is synthesized in eukaryotic cells primarily by the mitochondrial ATP synthase. ATP synthases operate by a rotary catalytic mechanism where proton translocation through the membrane ...
Anna Zhou   +7 more
doaj   +1 more source

The wheat chloroplast gene for CF0 subunit I of ATP synthase contains a large intron [PDF]

open access: bronze, 1985
Colin R. Bird   +6 more
openalex   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang   +3 more
wiley   +1 more source

PKA Phosphorylates the ATPase Inhibitory Factor 1 and Inactivates Its Capacity to Bind and Inhibit the Mitochondrial H+-ATP Synthase

open access: yesCell Reports, 2015
The mitochondrial H+-ATP synthase synthesizes most of cellular ATP requirements by oxidative phosphorylation (OXPHOS). The ATPase Inhibitory Factor 1 (IF1) is known to inhibit the hydrolase activity of the H+-ATP synthase in situations that compromise ...
Javier García-Bermúdez   +5 more
doaj   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

open access: yesAdvanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou   +10 more
wiley   +1 more source

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