Results 81 to 90 of about 615,643 (389)

Effect of rejection on electrophysiologic function of canine intestinal grafts: Correlation with histopathology and na-k-ATPase activity [PDF]

, 1995
To investigate whether electrophysiologic changes can detect the early onset and progress of intestinal rejection, changes in in vitro electrophysiologic function, intestinal histopathology, and Na-K-ATPase activity were studied in dogs.
Billiar T R, Charney A N, Charney A N, Cohen W B, Dennison A R, Esmann M, Grant D, Kirkman R L, Lee M D, Lee T K, Madara J L, Meijssen M AC, Millard P R, Murase N, Murase N, Nakahara S, Nakamura K, Nordgren S, Quigley J P, Rosemurgy A S, Schamaun M, Schiller W R, Schmid T, Schroeder P, Stanford W P, Todo S, Todo S, Yoshimi F   +27 more
core   +1 more source

Review: The HSP90 molecular chaperone—an enigmatic ATPase

Biopolymers, 2016
The HSP90 molecular chaperone is involved in the activation and cellular stabilization of a range of ‘client’ proteins, of which oncogenic protein kinases and nuclear steroid hormone receptors are of particular biomedical significance. Work over the last
L. Pearl
semanticscholar   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Influence of IP3 on ATPase activity of rat hepatocytes membrane vesicules after perfusion of liver by insulin-containing solution

Біологічні студії, 2012
The influence of IP3 on Ca2+-, Na+,K+-ATPase and basal Mg2+-ATPase activity of rat hepatocytes membranes was studied in control and after perfusion of liver by insulin-containing solution.
S. Bychkova, T. Chorna
doaj   +1 more source

Subunit interactions influence the biochemical and biological properties of Hsp104 [PDF]

, 2001
Point mutations in either of the two nucleotide-binding domains (NBD) of Hsp104 (NBD1 and NBD2) eliminate its thermotolerance function in vivo. In vitro, NBD1 mutations virtually eliminate ATP hydrolysis with little effect on hexamerization; analogous ...
Kowal, Anthony S, Lindquist, Susan L, Queitsch, Christine, Schirmer, Eric, Ware, Danielle M   +4 more
core   +2 more sources

Boundaries of photosynthesis: adaptations of carbon fixation in extreme environments

FEBS Open Bio, EarlyView.
Photosynthesis faces challenges from environmental extremes of temperature, pH, and salinity, limiting gas diffusion, modifying membrane fluidity, and destabilizing photochemical and biochemical reactions. Photosynthetic organisms have evolved unique adaptations overcoming these stresses and maintaining their photosynthetic activity.
Pere Aguiló‐Nicolau, Concepción Iñiguez, Sebastià Capó‐Bauçà, Jeroni Galmés   +3 more
wiley   +1 more source

Different Transport Pathways of Individual Precursor Proteins in Mitochondria [PDF]

, 1981
Transport of mitochondrial precursor proteins into mitochondria of Neurospora crassa was studied in a cellfree reconstituted system. Precursors were synthesized in a reticulocyte lysate programmed with Neurospora mRNA and transported into isolated ...
Allen E. H., Ambler R. P., Basile G., Conboy J. G., Cote C., Fisher W. R., Hackenberg H., Hallermayer G., Harmey M. A., Heller J., Jagow G., Korb H., Laemmli U. K., Lewin A., Maccechini M. -L., Maccechini M. -L., Michel R., Mihara K., Mori M., Nelson N, Paul K. G., Pelham H. R. B., Raymond Y., Schatz G., Schmelzer E., Sebald W., Shore G. S., Sonderegger P., Tzagoloff A., Zimmermann R., Zimmermann R., Zimmermann R.   +31 more
core   +1 more source

Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas, Cristina Domínguez‐González, Daniel Natera‐de Benito, Solange Kapetanovic, Aurelio Hernández‐Laín, Berta Estévez‐Arias, Laura Llansó, Carlos Ortez, Cristina Jou, Itxaso Martí‐Carrera, Arístides López‐Márquez, Maria José Rodríguez, Laura González‐Mera, Velina Nedkova, Roberto Fernández‐Torrón, Benjamín Rodríguez‐Santiago, Cecília Jimenez‐Mallebrera, Raul Juntas‐Morales, Adolfo López‐de Munain, Jordi Surrallés, Andrés Nascimento, Eduard Gallardo, Montse Olivé, Pia Gallano, Lidia González‐Quereda   +24 more
wiley   +1 more source

Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1. [PDF]

, 2013
One third of inherited genetic diseases are caused by mRNAs harboring premature termination codons as a result of nonsense mutations. These aberrant mRNAs are degraded by the Nonsense-Mediated mRNA Decay (NMD) pathway.
Bracho, Dina P, Cajigas, Iván J, Correa, María E, Estrella, Luis A, González, Carlos I, González-Feliciano, José A, Lasalde, Clarivel, León, Alfredo J, Rivera, Andrea V, Rodríguez-Cruz, Eva N, Vega, Irving E, Wilkinson, Miles F   +11 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source