Results 101 to 110 of about 2,145,052 (301)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Depressive Symptoms in Late Pregnancy Disrupt Attentional Processing of Negative–Positive Emotion: An Eye-Movement Study

Frontiers in Psychiatry, 2019
This study investigated biases for negative–positive information in component processes of visual attention (initial shift vs. maintenance of gaze) among women in late pregnancy with or without depressive symptoms.
Weina Tang, Ciqing Bao, Ling Xu, Jie Zhu, Wenqian Feng, Wenmiao Zhang, Cong Lin, Lan Chen, Qianqian Cheng, Penghao Ding, Meixi Zhou, Ying Bao, Xin Yu, Ke Zhao, Jincai He, Jincai He   +15 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Approaching Cognitive Behavior Therapy For Generalized Anxiety Disorder From A Cognitive Process Perspective

Frontiers in Psychiatry, 2019
Generalized anxiety disorder (GAD), with uncontrollable worry at its core, is a common psychological disorder with considerable individual and societal costs.
Colette R. Hirsch, Colette R. Hirsch, Sarah Beale, Nick Grey, Sheena Liness, Sheena Liness   +5 more
doaj   +1 more source

Instructed fear stimuli bias visual attention

Acta Psychologica, 2018
We investigated whether stimuli merely instructed to be fear-relevant can bias visual attention, even when the fear relation was never experienced before. Participants performed a dot-probe task with pictures of naturally fear-relevant (snake or spider) or -irrelevant (bird or butterfly) stimuli.
Deltomme, Berre, Mertens, Gaëtan, Tibboel, Helen, Braem, Senne   +3 more
openaire   +4 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

The Early Facilitative and Late Contextual Specific Effect of the Color Red on Attentional Processing

Frontiers in Human Neuroscience, 2018
Many studies have proved that color represents a variety of emotionally meaningful information. Researchers have proposed that context information endows colors with different associated meanings, and elicits corresponding behavior. Others have contended
Tao Xia, Zhengyang Qi, Jiaxin Shi, Mingming Zhang, Wenbo Luo   +4 more
doaj   +1 more source

Mass functions and bias of dark matter halos [PDF]

, 2009
We revisit the study of the mass functions and the bias of dark matter halos. Focusing on the limit of rare massive halos, we point out that exact analytical results can be obtained for the large-mass tail of the halo mass function.
Bardeen, Barkana, Bernardeau, Bernardeau, Bernardeau, Betancort-Rijo, Betancort-Rijo, Blanchard, Bond, Bond, Borgani, Cuesta, Dalal, Diaferio, Dolag, Duffy, Efstathiou, Einasto, Evrard, Fry, Gao, Gurbatov, Hamana, Jenkins, Kaiser, McCracken, Mo, Mo, Navarro, P. Valageas, Padilla, Peebles, Politzer, Prada, Press, Reed, Reed, Sheth, Sheth, Tinker, Trujillo, Valageas, Valageas, Valageas, Valageas, Wang, Warren, Zeldovich   +47 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A Neurophysiological and Behavioral Assessment of Interventions Targeting Attention Bias and Sense of Control in Binge Drinking

Frontiers in Human Neuroscience, 2019
Attention bias modification (ABM) can decrease the selective visual attention paid to alcohol-related cues but has not been found to reliably reduce alcohol craving.
Jessica E. Langbridge, Jessica E. Langbridge, Richard D. Jones, Richard D. Jones, Juan J. Canales   +4 more
doaj   +1 more source