Results 101 to 110 of about 447,511 (284)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Uplifting Moods: Augmented Reality-Based Gamified Mood Intervention App with Attention Bias Modification

open access: yesSoftware
Attention Bias Modification (ABM) is a cost-effective mood intervention that has the potential to be used in daily settings beyond clinical environments. However, its interactivity and user engagement are known to be limited and underexplored.
Yun Jung Yeh, Sarah S. Jo, Youngjun Cho
doaj   +1 more source

Assumptions of IV Methods for Observational Epidemiology

open access: yes, 2010
Instrumental variable (IV) methods are becoming increasingly popular as they seem to offer the only viable way to overcome the problem of unobserved confounding in observational studies.
Didelez, Vanessa   +2 more
core   +1 more source

Examination of a Parent-Assisted, Friendship-Building Program for Adolescents with ADHD [PDF]

open access: yes, 2015
Attention-Deficit/Hyperactivity Disorder (ADHD) is a common childhood disorder that often contributes to impairment in multiple domains, including peer functioning.
Gardner, Denise Marie
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Working memory load elicits attentional bias to threat [PDF]

open access: yes, 2014
Anxious individuals tend to show attentional bias to threats and dangers; this is usually in-terpreted as a specific bias in threat-processing. However, they also tend to show general working memory and cognitive control impairments. We hypothesised that
Booth, Robert, Sharma, Dinkar
core  

Complete recovery from anxiety disorders following Cognitive Behavioural Therapy in children and adolescents: a meta analysis [PDF]

open access: yes, 2017
Cognitive Behavior Therapy (CBT) is a well-established treatment for childhood anxiety disorders. Meta-analyses have concluded that approximately 60% of children recover following treatment, however these include studies using a broad range of diagnostic
Cooper, Peter   +6 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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