Results 31 to 40 of about 32,506 (196)

Senile Systemic Amyloidosis: Clinical Features at Presentation and Outcome [PDF]

, 2013
Background Cardiac amyloidosis is a fatal disease whose prognosis and treatment rely on identification of the amyloid type. In our aging population transthyretin amyloidosis (ATTRwt) is common and must be differentiated from other amyloid types.
Banypersad, SM, Whelan, CJ, Lachmann, HJ, Gillmore, JD, Gibbs, SD, Hawkins, PN, McCarthy, CA, Sattianayagam, P, Rowczenio, D, Wechalekar, A, Venner, CP, Petrie, A, Dungu, J, Wassef, N, Pinney, JH, Gilbertson, JA   +15 more
core   +1 more source

Best Practices in Specialized Amyloidosis Centers in the United States: A Survey of Cardiologists, Nurses, Patients, and Patient Advocates

Clinical Medicine Insights: Cardiology, 2021
Background: Because transthyretin amyloid cardiomyopathy (ATTR-CM) poses unique diagnostic and therapeutic challenges, referral of patients with known or suspected disease to specialized amyloidosis centers is recommended.
Jose Nativi-Nicolau, Nitasha Sarswat, Johana Fajardo, Muriel Finkel, Younos Abdulsattar, Adam Castaño, Lori Klein, Alexandra Haddad-Angulo   +7 more
doaj   +1 more source

CMR-Based Differentiation of AL and ATTR Cardiac Amyloidosis [PDF]

, 2014
ObjectivesThis study was devised to describe the different cardiac magnetic resonance (CMR) appearances in light chain amyloid (AL) and transthyretin-related amyloidosis (ATTR).BackgroundCMR is increasingly used to investigate patients with suspected ...
Valencia, Oswaldo, Gibbs, Simon D.J., Rowczenio, Dorota, Hawkins, Philip N., Wechalekar, Ashutosh, Lachmann, Helen J., Anderson, Lisa J., Gilbertson, Janet A., Dungu, Jason N., Pinney, Jennifer H., Whelan, Carol J., Gillmore, Julian D.   +11 more
core   +1 more source

A case of fatal familial edema

IHJ Cardiovascular Case Reports, 2023
Cardiac amyloidosis is an often-underdiagnosed cause of heart failure, and associated morbidity and mortality. AL (Primary amyloidosis) and ATTR (Amyloidosis, hereditary, transthyretin-related) variants most commonly affect the heart amongst the ...
Sriram Easwaran, Milind Phadke, Nitin Burkule, Ashwin Dalal, Pratap Nathani   +4 more
doaj   +1 more source

Quality of life in ATTR amyloidosis [PDF]

Orphanet Journal of Rare Diseases, 2015
Methods As part of a protocolised model of care involving comprehensive annual clinical evaluation (including DPD scintigraphy, echocardiography, ECG, neurological testing, cardiac magnetic resonance imaging (CMR), 6-minute walk test and blood tests), patients completed the KCCQ and SF-36 questionnaires.
Lane, Thirusha, Bangova, Alica, Fontana, Marianna, Hutt, David F, Strehina, Svetla G, Whelan, Carol J, Hawkins, Philip N, Gillmore, Julian D   +7 more
openaire   +1 more source

Involvement of cranial nerves in ATTR Ile127Val amyloidosis

European Journal of Medical Genetics, 2022
The involvement of cranial nerves is rare in ATTR amyloidosis. However, involvement has occasionally been reported in the p.Val50Met variant, the most commonly studied worldwide. On the other hand, in ATTR p.Ile127Val, an uncommon variant, the cranial nerves IX, X, and XII, are frequently involved.
Jemima A. da Silva Batista, Luiza R. Carrera, Adriele R.F. Viriato, Marco Antônio C. Novaes, Renato José L. de Morais, Francisco T.O. Oliveira, Wilson Marques, Marcela Câmara Machado- Costa   +7 more
openaire   +3 more sources

Utility of Genetic Testing in Patients with Transthyretin Amyloid Cardiomyopathy: A Brief Review

Biomedicines, 2023
Transthyretin amyloid cardiomyopathy (ATTR-CM) is an increasingly diagnosed condition. Although wild-type transthyretin amyloidosis (ATTRwt) is the most common ATTR-CM, hereditary transthyretin amyloidosis (ATTRv) may also occur.
Ana-Maria Merino-Merino, Jorge Labrador-Gomez, Ester Sanchez-Corral, Pedro-David Delgado-Lopez, Jose-Angel Perez-Rivera   +4 more
doaj   +1 more source

Disease progression in cardiac transthyretin amyloidosis is indicated by serial calculation of National Amyloidosis Centre transthyretin amyloidosis stage

ESC Heart Failure, 2020
Aims Cardiac transthyretin amyloidosis (ATTR‐CM) is a progressive and fatal condition. Prognosis can be determined at diagnosis according to the National Amyloidosis Centre (NAC) transthyretin amyloidosis (ATTR) stage.
Steven Law, Aviva Petrie, Liza Chacko, Oliver C. Cohen, Sriram Ravichandran, Janet A. Gilbertson, Dorota Rowczenio, Ashutosh Wechalekar, Ana Martinez‐Naharro, Helen J. Lachmann, Carol J. Whelan, David F. Hutt, Philip N. Hawkins, Marianna Fontana, Julian D. Gillmore   +14 more
doaj   +1 more source

Clinical and Genotype Characteristics and Symptom Migration in Patients With Mixed Phenotype Transthyretin Amyloidosis from the Transthyretin Amyloidosis Outcomes Survey

Cardiology and Therapy, 2023
Introduction Transthyretin amyloidosis (ATTR amyloidosis) is primarily associated with a cardiac or neurologic phenotype, but a mixed phenotype is increasingly described.
Juan González-Moreno, Angela Dispenzieri, Martha Grogan, Teresa Coelho, Ivailo Tournev, Márcia Waddington-Cruz, Jonas Wixner, Igor Diemberger, Pablo Garcia-Pavia, Doug Chapman, Pritam Gupta, Oliver Glass, Leslie Amass, the THAOS investigators   +13 more
doaj   +1 more source

Antibody-Associated Reversal of ATTR Amyloidosis–Related Cardiomyopathy

New England Journal of Medicine, 2023
No ...
Marianna Fontana, Janet Gilbertson, Guglielmo Verona, Mattia Riefolo, Ivana Slamova, Ornella Leone, Dorota Rowczenio, Nicola Botcher, Adam Ioannou, Rishi K. Patel, Yousuf Razvi, Ana Martinez-Naharro, Carol J. Whelan, Lucia Venneri, Amanda Duhlin, Diana Canetti, Stephan Ellmerich, James C. Moon, Peter Kellman, Raya Al-Shawi, Laura McCoy, J. Paul Simons, Philip N. Hawkins, Julian D. Gillmore   +23 more
openaire   +5 more sources