Results 61 to 70 of about 461,407 (167)

Molecular Barriers to Zoonotic Transmission of Prions

open access: yesEmerging Infectious Diseases, 2014
The risks posed to human health by individual animal prion diseases cannot be determined a priori and are difficult to address empirically. The fundamental event in prion disease pathogenesis is thought to be the seeded conversion of normal prion protein
Marcelo A. Barria   +8 more
doaj   +1 more source

Atypical variants of bovine spongiform encephalopathy: rare diseases with consequences for BSE surveillance and control [PDF]

open access: yes, 2016
Occurring for the first time in 1986 in the United Kingdom, bovine spongiform encephalopathy (BSE), the so-called “mad-cow disease”, has had unprecedented consequences in veterinary public health.
Serra, Fabienne Heirangi   +2 more
core   +2 more sources

Transgenic Mice Expressing Porcine Prion Protein Resistant to Classical Scrapie but Susceptible to Sheep Bovine Spongiform Encephalopathy and Atypical Scrapie

open access: yesEmerging Infectious Diseases, 2009
How susceptible pigs are to infection with sheep prions is unknown. We show, through transmission experiments in transgenic mice expressing porcine prion protein (PrP), that the susceptibility of this mouse model to bovine spongiform encephalopathy (BSE)
Juan-Carlos Espinosa   +8 more
doaj   +1 more source

EU-approved rapid tests for bovine spongiform encephalopathy detect atypical forms: a study for their sensitivities. [PDF]

open access: yesPLoS ONE, 2012
Since 2004 it become clear that atypical bovine spongiform encephalopthies (BSEs) exist in cattle. Whenever their detection has relied on active surveillance plans implemented in Europe since 2001 by rapid tests, the overall and inter-laboratory ...
Daniela Meloni   +9 more
doaj   +1 more source

Discrimination of Classical and Atypical BSE by a Distinct Immunohistochemical PrPSc Profile

open access: yesPathogens, 2023
Bovine spongiform encephalopathy (BSE) belongs to the group of transmissible spongiform encephalopathies and is associated with the accumulation of a pathological isoform of the host-encoded glycoprotein, designated prion protein (PrPSc).
Christine Fast   +9 more
doaj   +1 more source

Advice on animal and public health risks of insects reared on former foodstuffs as raw material for animal feed

open access: yesFood Risk Assess Europe, Volume 4, Issue 1, January 2026.
Abstract In the coming decades, there is expected to be a sharply increased demand for dietary proteins for humans and animals. As a result, there is an increasing focus on reared insects as a new source of protein. According to the Ministry of Agriculture, Nature and Food Quality (LNV), the use of food chain residual flows such as former foodstuffs as
L.F.F. Kox, D.T.H.M. Sijm
wiley   +1 more source

Scientific Opinion on BSE/TSE infectivity in small ruminant tissues

open access: yesEFSA Journal, 2010
The objectives addressed were i) to provide an update on TSE (Transmissible Spongiform Encephalopathy) infectivity distribution in small ruminant tissues; and ii) to indicate based on the current epidemiological situation as regards to BSE (Bovine ...
EFSA Panel on Biological Hazards (BIOHAZ)
doaj   +1 more source

Atypical Scrapie Prions from Sheep and Lack of Disease in Transgenic Mice Overexpressing Human Prion Protein

open access: yesEmerging Infectious Diseases, 2013
Public and animal health controls to limit human exposure to animal prions are focused on bovine spongiform encephalopathy (BSE), but other prion strains in ruminants may also have zoonotic potential.
Jonathan D.F. Wadsworth   +11 more
doaj   +1 more source

Lessons learned and lingering uncertainties after seven years of chronic wasting disease management in Norway

open access: yesWildlife Biology, Volume 2025, Issue 5, September 2025.
Chronic wasting disease (CWD) is well known among cervids in North America. Nevertheless, management faced different types and degrees of uncertainty when CWD was first detected in reindeer Rangifer tarandus in Nordfjella, Norway in 2016. We present a timeline of the efforts to control CWD, and identify how the process, measurement, environmental, and ...
Atle Mysterud   +3 more
wiley   +1 more source

Four types of scrapie in goats differentiated from each other and bovine spongiform encephalopathy by biochemical methods

open access: yesVeterinary Research, 2019
Scrapie in goats has been known since 1942, the archetype of prion diseases in which only prion protein (PrP) in misfolded state (PrPSc) acts as infectious agent with fatal consequence.
Jan P. M. Langeveld   +21 more
doaj   +1 more source

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