Results 61 to 70 of about 461,407 (167)
Molecular Barriers to Zoonotic Transmission of Prions
The risks posed to human health by individual animal prion diseases cannot be determined a priori and are difficult to address empirically. The fundamental event in prion disease pathogenesis is thought to be the seeded conversion of normal prion protein
Marcelo A. Barria +8 more
doaj +1 more source
Atypical variants of bovine spongiform encephalopathy: rare diseases with consequences for BSE surveillance and control [PDF]
Occurring for the first time in 1986 in the United Kingdom, bovine spongiform encephalopathy (BSE), the so-called “mad-cow disease”, has had unprecedented consequences in veterinary public health.
Serra, Fabienne Heirangi +2 more
core +2 more sources
How susceptible pigs are to infection with sheep prions is unknown. We show, through transmission experiments in transgenic mice expressing porcine prion protein (PrP), that the susceptibility of this mouse model to bovine spongiform encephalopathy (BSE)
Juan-Carlos Espinosa +8 more
doaj +1 more source
EU-approved rapid tests for bovine spongiform encephalopathy detect atypical forms: a study for their sensitivities. [PDF]
Since 2004 it become clear that atypical bovine spongiform encephalopthies (BSEs) exist in cattle. Whenever their detection has relied on active surveillance plans implemented in Europe since 2001 by rapid tests, the overall and inter-laboratory ...
Daniela Meloni +9 more
doaj +1 more source
Discrimination of Classical and Atypical BSE by a Distinct Immunohistochemical PrPSc Profile
Bovine spongiform encephalopathy (BSE) belongs to the group of transmissible spongiform encephalopathies and is associated with the accumulation of a pathological isoform of the host-encoded glycoprotein, designated prion protein (PrPSc).
Christine Fast +9 more
doaj +1 more source
Abstract In the coming decades, there is expected to be a sharply increased demand for dietary proteins for humans and animals. As a result, there is an increasing focus on reared insects as a new source of protein. According to the Ministry of Agriculture, Nature and Food Quality (LNV), the use of food chain residual flows such as former foodstuffs as
L.F.F. Kox, D.T.H.M. Sijm
wiley +1 more source
Scientific Opinion on BSE/TSE infectivity in small ruminant tissues
The objectives addressed were i) to provide an update on TSE (Transmissible Spongiform Encephalopathy) infectivity distribution in small ruminant tissues; and ii) to indicate based on the current epidemiological situation as regards to BSE (Bovine ...
EFSA Panel on Biological Hazards (BIOHAZ)
doaj +1 more source
Public and animal health controls to limit human exposure to animal prions are focused on bovine spongiform encephalopathy (BSE), but other prion strains in ruminants may also have zoonotic potential.
Jonathan D.F. Wadsworth +11 more
doaj +1 more source
Chronic wasting disease (CWD) is well known among cervids in North America. Nevertheless, management faced different types and degrees of uncertainty when CWD was first detected in reindeer Rangifer tarandus in Nordfjella, Norway in 2016. We present a timeline of the efforts to control CWD, and identify how the process, measurement, environmental, and ...
Atle Mysterud +3 more
wiley +1 more source
Scrapie in goats has been known since 1942, the archetype of prion diseases in which only prion protein (PrP) in misfolded state (PrPSc) acts as infectious agent with fatal consequence.
Jan P. M. Langeveld +21 more
doaj +1 more source

