Results 91 to 100 of about 12,787 (210)

Clinical case of thrombotic microangiopathy in obstetric practice

open access: yesСеченовский вестник, 2017
Trombotic microangiopathy is heterogeneous group of the diseases united by a community of a histological and clinical implications at difference of pathogenetic mechanisms, presents clinical-morphological syndrome characterizing a lesion of vessels of a ...
M. N. Mochalova   +5 more
doaj  

A Case of Carfilzomib-Induced Atypical Hemolytic Uremic Syndrome

open access: yesAnnals of Internal Medicine: Clinical Cases
Atypical hemolytic uremic syndrome (aHUS) is a rare non-Shiga toxin thrombotic microangiopathy caused by uncontrolled activation of the alternative complement pathway.
Kwasi Opare-Addo   +3 more
doaj   +1 more source

ATYPICAL HEMOLYTIC-UREMIC SYNDROME IN THE FEMALE PATIENT WITH CONCURRENT MENOMETRORRHAGIA (clinical case)

open access: yesВестник анестезиологии и реаниматологии, 2018
The article describes the follow-up over the development of atypical hemolytic-uremic syndrome in the female patient suffering menometrorrhagia which manifested with concurrent metrorrhagia and was accompanied with acute renal failure.
A. V. Pyregov   +3 more
doaj   +1 more source

The Complement System in ANCA‐Associated Vasculitis: Mechanistic Insights, Therapeutic Horizons, and Unmet Clinical Needs

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Complement activation, particularly via the alternative pathway, drives inflammation and organ damage in ANCA‐associated vasculitis. This review highlights mechanistic insights, tissue and biomarker evidence, and clinical implications of targeting the C5a–C5aR1 axis.
Kehinde Sunmboye, Pauline Millan
wiley   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 149-175, January 2026.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca   +2 more
wiley   +1 more source

Safety and efficacy of eculizumab in adult and pediatric patients with aHUS, with or without baseline dialysis [PDF]

open access: yes, 2015
C
Hourmant, Maryvonne   +5 more
core   +1 more source

Factor H gene variants in Japanese: Its relation to atypical hemolytic uremic syndrome [PDF]

open access: yes, 2011
Mutations and polymorphisms of factor H gene (FH1) are known to be closely involved in the developmentof atypical hemolytic uremic syndrome (aHUS). Several groups have identified disease risk mutations andpolymorphisms of FH1 for the development of aHUS,
Fujihara Noriko   +10 more
core   +1 more source

[Hemolytic uremic syndrome with an atypical presentation].

open access: yesRevue medicale de Liege, 2010
The hemolytic uremic syndrome (HUS) is rare and of guarded prognosis in adults. It expresses a renal thrombotic microangiopathy. We report the case of a young patient whose clinical presentation and exploration make a diagnosis of HUS likely. The atypical presentation provides an opportunity not only to discuss all diagnostic elements based on recent ...
NOGUE KAMDJE, Alain   +3 more
openaire   +2 more sources

Shiga toxin/verocytotoxin-producing Escherichia coli infections: practical clinical perspectives [PDF]

open access: yes, 2014
Escherichia coli strains that produce Shiga toxins/verotoxins are rare, but important, causes of human disease. They are responsible for a spectrum of illnesses that range from the asymptomatic to the life-threatening hemolytic-uremic ...
Davis, T. K   +2 more
core   +2 more sources

Complement System Part II: Role in Immunity [PDF]

open access: yes, 2015
International audienceThe complement system has been considered for a long time as a simple lytic cascade, aimed to kill bacteria infecting the host organism.
Fremeaux-Bacchi, Veronique   +4 more
core   +6 more sources

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