Results 71 to 80 of about 8,784 (177)

Multiple Myeloma as the Underlying Cause of Thrombotic Microangiopathy Leading to Acute Kidney Injury: Revisiting a Very Rare Entity

Journal of Investigative Medicine High Impact Case Reports, 2017
Thrombotic microangiopathy (TMA) describes a pathological process of microvascular thrombosis, consumptive thrombocytopenia, and microangiopathic hemolytic anemia, leading to end-organ ischemia and infarction, affecting particularly the kidney and brain.
Savneek Chugh MD, Asim Kichloo MD, Firas Jafri MD, Liga Yusvirazi MD, Robert Lerner MD   +4 more
doaj   +1 more source

Factor I autoantibodies in patients with atypical hemolytic uremic syndrome: disease-associated or an epiphenomenon?

, 2012
BACKGROUND AND OBJECTIVES: Atypical hemolytic uremic syndrome is a disease associated with mutations in the genes encoding the complement regulators factors H and I.
Pietro Roversi, Hunze, EM, Christine M. Hayes, Timothy H. J. Goodship, Susan Lea, Bennaceur, K, Kevin J. Marchbank, Eva-Maria Hunze, Marchbank, KJ, Moore, Iain, Strain, Lisa, David Kavanagh, Ward, Roy, Marchbank, Kevin J., Lea, Susan, Moore, I, Nick Plant, Roy Ward, Corina Nailescu, Lea, S, Strain, L, Goodship, TH, Anderson, H, Karim Bennaceur, Plant, N, Bennaceur, Karim, Hayes, CM, Iain Moore, Hayes, Christine M., Pappworth, IY, Isabel Y. Pappworth, Kavanagh, David, Plant, Nick, Anderson, Holly, Nailescu, Corina, Hunze, Eva-Maria, Goodship, Timothy H. J., Nailescu, C, Pappworth, Isabel Y., Holly Anderson, Ward, R, Kavanagh, D, Roversi, Pietro, Lisa Strain, Roversi, P   +44 more
core   +1 more source

Bevacizumab-induced atypical hemolytic uremic syndrome and treatment with eculizumab

, 2018
Bevacizumab (Avastin) is a recombinant humanized monoclonal antibody used for the management of various solid malignancies including colorectal, lung, brain, renal, and ovarian cancers as well as age-related macular degeneration of the eye.
Daulath Singh, Anusha Vakiti, Kelly W Fitzpatrick, Ravi Pilla, Muhamad Alhaj-Moustafa   +4 more
core   +1 more source

Hemolytic Uremic Syndrome in Pregnancy and Postpartum

, 2017
BACKGROUND: Pregnancy is associated with various forms of thrombotic microangiopathy, including hemolytic uremic syndrome. A previous small French study suggested that pregnancy-associated hemolytic uremic syndrome was to be included in the spectrum of ...
Remuzzi, G., Provot, F., Chantal Loirat, Noris, M., Giuseppe Remuzzi, Delmas, Y., Fakhouri, F., Mele, C., Yahsou Delmas, Wong, E. K. S., David Kavanagh, Vicky Brocklebank, Kavanagh, D., Edwin K.S. Wong, Loirat, C., Fadi Fakhouri, Marina Noris, Véronique Frémeaux-Bacchi, Bruel, A., François Provôt, Brocklebank, V., Alexandra Bruel, Fremeaux-Bacchi, V., Bresin, E., Caterina Mele, Elena Bresin   +25 more
core   +1 more source

Hemolytic uremic syndrome and IgA nephropathy in a child: Coincidence or not?

The Turkish Journal of Pediatrics, 2018
A previously healthy 18-month old boy, presenting with diarrhea, anemia, thrombocytopenia and acute renal failure was admitted to our hospital. Hemolytic uremic syndrome (HUS) was diagnosed with his clinical and laboratory findings.
Serra Sürmeli-Döven, Ali Delibaş, İclal Gürses, Uğur Raşit Kayacan, Banu Coşkun-Yılmaz, Kaan Esen, Emine Korkmaz, Fatih Özaltın   +7 more
doaj   +1 more source

Current treatment of atypical hemolytic uremic syndrome

Intractable & Rare Diseases Research, 2014
Tremendous advances have been made in understanding the pathogenesis of atypical Hemolytic Uremic Syndrome (aHUS), an extremely rare disease. Insights into the molecular biology of aHUS resulted in rapid advances in treatment with eculizumab (Soliris(®), Alexion Pharmaceuticals Inc.).
S. Kaplan, Bernard, L. Ruebner, Rebecca, M. Spinale, Joann, Copelovitch, Lawrence   +3 more
openaire   +3 more sources

How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome

, 2014
Thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic uraemic syndrome (aHUS) are acute, rare life-threatening thrombotic microangiopathies that require rapid diagnosis and treatment.
Goodship, T, Scully, M
core  

Rare Presentation of Atypical Hemolytic Uremic Syndrome in an Adult

, 2021
Thrombotic microangiopathies (TMA) are disorders characterized by microangiopathic hemolytic anemia, thrombocytopenia, and microthrombi leading to organ dysfunction.
Cook, Christopher, Fatima, Zainab, Thomas, Akesh, Alhabhbeh, Ammar A.   +3 more
core   +1 more source

Clinical case of thrombotic microangiopathy in obstetric practice

Сеченовский вестник, 2017
Trombotic microangiopathy is heterogeneous group of the diseases united by a community of a histological and clinical implications at difference of pathogenetic mechanisms, presents clinical-morphological syndrome characterizing a lesion of vessels of a ...
M. N. Mochalova, T. E. Belokrinitskaya, T. V. Haven, E. M. Shifman, K. G. Shapovalov, S. V. Kostromitin   +5 more
doaj  

A Case of Carfilzomib-Induced Atypical Hemolytic Uremic Syndrome

Annals of Internal Medicine: Clinical Cases
Atypical hemolytic uremic syndrome (aHUS) is a rare non-Shiga toxin thrombotic microangiopathy caused by uncontrolled activation of the alternative complement pathway.
Kwasi Opare-Addo, Sammudeen Ibrahim, Basilio Addo, Jorge Chancay Rodriguez   +3 more
doaj   +1 more source