Results 81 to 90 of about 12,787 (210)
ABSTRACT Severe malaria remains a major cause of acute kidney injury and multiorgan failure in endemic regions, often requiring renal replacement therapy. However, access to dialysis is limited in many resource‐constrained settings, making outcomes highly dependent on early diagnosis and effective antimalarial treatment. We report a 32‐year‐old man who
Tamirat Godebo Woyimo +8 more
wiley +1 more source
SUCCESSFUL TREATMENT FOR ATYPICAL HEMOLYTIC UREMIC SYNDROME IN A PUERPERA
Objective: to show the problems of differential diagnosis and treatment of atypical hemolytic-uremic syndrome in a 23-year-old patient.Results. Eculizumab (Soliris), (Alexon Pharmaceuticals Inc., USA) that is a glycosylated humanized monoclonal antibody ...
O. N. Ulitkina +4 more
doaj +1 more source
Thrombomodulin enhances complement regulation through strong affinity interactions with factor H and C3b-Factor H complex [PDF]
Introduction Coagulation and complement systems are simultaneously activated at sites of tissue injury, leading to thrombin generation and opsonisation with C3b.
Baerga-Ortiz +58 more
core +2 more sources
Exercise‐induced vasculitis with histological and genetic evidence of complement involvement
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Massimo Cugno +6 more
wiley +1 more source
ABSTRACT In endemic areas, acute undifferentiated febrile illness has a wide differential with overlapping features that can lead to misdiagnosis. Although triple co‐infection with scrub typhus, dengue, and leptospirosis is extremely rare, high clinical suspicion and early detection are vital to avoid delayed treatment, multi‐organ dysfunction, and ...
Sulav Kumar Jha +5 more
wiley +1 more source
Intravascular Large B-Cell Lymphoma Presenting as Dementia and Hemolytic Anemia [PDF]
Background: Intravascular lymphoma (IVL) is an uncommon disease characterized by atypical lymphoid cells growing inside the lumina of small vessels. The diversity of clinical presentation due to possible involvement of multiple organs often complicates ...
Ahle, Guido +6 more
core +1 more source
Hemolytic uremic syndrome and IgA nephropathy in a child: Coincidence or not?
A previously healthy 18-month old boy, presenting with diarrhea, anemia, thrombocytopenia and acute renal failure was admitted to our hospital. Hemolytic uremic syndrome (HUS) was diagnosed with his clinical and laboratory findings.
Serra Sürmeli-Döven +7 more
doaj +1 more source
Meningococcal Serogroup Y Meningitis Reveals Inborn Factor B Deficiency
We report a novel case of complete complement Factor B deficiency revealed by invasive meningococcal disease. Using combined functional and genetic analyses, we demonstrate that loss of Factor B abolishes alternative pathway activity despite detectable protein levels. These findings provide a mechanistic framework relevant to complement diagnostics and
Camille Bougeard +9 more
wiley +1 more source
Current treatment of atypical hemolytic uremic syndrome
Tremendous advances have been made in understanding the pathogenesis of atypical Hemolytic Uremic Syndrome (aHUS), an extremely rare disease. Insights into the molecular biology of aHUS resulted in rapid advances in treatment with eculizumab (Soliris(®), Alexion Pharmaceuticals Inc.).
Bernard S, Kaplan +3 more
openaire +3 more sources

