Results 121 to 130 of about 25,762 (279)

The long-acting C5 inhibitor, ravulizumab, is efficacious and safe in pediatric patients with atypical hemolytic uremic syndrome previously treated with eculizumab

open access: yesPediatric nephrology (Berlin, West), 2020
Atypical hemolytic uremic syndrome (aHUS) is a rare, complement-mediated disease associated with poor outcomes if untreated. Ravulizumab, a long-acting C5 inhibitor developed through minimal, targeted modifications to eculizumab was recently approved for
Kazuki Tanaka   +7 more
semanticscholar   +1 more source

Evaluation of Hypertension in Pediatric Hemolytic Uremic Syndrome (A Cross‐Sectional Study)

open access: yesHealth Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background Hemolytic uremic syndrome (HUS), particularly the Shiga toxin‐producing Escherichia coli (STEC)‐associated subtype, is a major cause of acute kidney injury [AKI] in children. Although hypertension (HTN) is a recognized complication of HUS, its prevalence and related risk factors in these children are particularly poorly studied ...
Mahdi Banaei Nourmohammadi   +5 more
wiley   +1 more source

Intravascular Large B-Cell Lymphoma Presenting as Dementia and Hemolytic Anemia [PDF]

open access: yes, 2010
Background: Intravascular lymphoma (IVL) is an uncommon disease characterized by atypical lymphoid cells growing inside the lumina of small vessels. The diversity of clinical presentation due to possible involvement of multiple organs often complicates ...
Ahle, Guido   +6 more
core   +1 more source

Investigation of the Abundance of Escherichia coli and Staphylococcus aureus (Including Virulence Gene Profiles) and Heavy Metal Contamination in Camel Milk

open access: yesVeterinary Medicine and Science, Volume 11, Issue 6, November 2025.
GRAPHICAL ABSTRACT Camel milk exhibited Staphylococcus aureus and Escherichia coli contamination with associated antibiotic resistance and virulence genes. Concurrently, heavy metal levels (Pb, As and Cd) in these samples were low and below safety limits, providing a comprehensive assessment of dual hazards in this vital food source.
Elahe Yazdanian Ghahfarokhi   +3 more
wiley   +1 more source

Clinical case of thrombotic microangiopathy in obstetric practice

open access: yesСеченовский вестник, 2017
Trombotic microangiopathy is heterogeneous group of the diseases united by a community of a histological and clinical implications at difference of pathogenetic mechanisms, presents clinical-morphological syndrome characterizing a lesion of vessels of a ...
M. N. Mochalova   +5 more
doaj  

Hemolytic uremic syndrome and IgA nephropathy in a child: Coincidence or not?

open access: yesThe Turkish Journal of Pediatrics, 2018
A previously healthy 18-month old boy, presenting with diarrhea, anemia, thrombocytopenia and acute renal failure was admitted to our hospital. Hemolytic uremic syndrome (HUS) was diagnosed with his clinical and laboratory findings.
Serra Sürmeli-Döven   +7 more
doaj   +1 more source

The global aHUS registry: methodology and initial patient characteristics [PDF]

open access: yes, 2015
Background: Atypical hemolytic uremic syndrome (aHUS) is a rare, genetically-mediated systemic disease most often caused by chronic, uncontrolled complement activation that leads to systemic thrombotic microangiopathy (TMA) and renal and other end-organ ...
Ardissino, Gianluigi   +11 more
core   +2 more sources

CD59, Disulphide‐Locked Human C9 and Horse C9 Inhibit Human Membrane Attack Complex Assembly by Similar Mechanisms

open access: yesImmunology, Volume 176, Issue 3, Page 363-372, November 2025.
The membrane attack complex (MAC) is formed by the stepwise assembly of five proteins: C5b, C6, C7, C8 and C9. MAC plays a key role in driving inflammation in numerous diseases. This study compares the inhibitory mechanisms of MAC assembly by soluble CD59 (sCD59), a disulphide‐locked C9 mutant (C9lock) and horse C9 (HoC9).
Rebekah S. Cooke   +5 more
wiley   +1 more source

A Case of Carfilzomib-Induced Atypical Hemolytic Uremic Syndrome

open access: yesAnnals of Internal Medicine: Clinical Cases
Atypical hemolytic uremic syndrome (aHUS) is a rare non-Shiga toxin thrombotic microangiopathy caused by uncontrolled activation of the alternative complement pathway.
Kwasi Opare-Addo   +3 more
doaj   +1 more source

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