Safety and efficacy of eculizumab in adult and pediatric patients with aHUS, with or without baseline dialysis [PDF]
C
Hourmant, Maryvonne +5 more
core +1 more source
Actualización en síndrome hemolítico urémico atípico: diagnóstico y tratamiento. Documento de consenso [PDF]
Trobareu una actualització (2015) d'aquest document a: http://hdl.handle.net/2445/99427Haemolytic uraemic syndrome (HUS) is a clinical entity defined as the triad of nonimmune haemolytic anaemia, thrombocytopenia, and acute renal failure, in which the ...
Arias, Manuel +9 more
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Atypical Hemolytic‐Uremic Syndrome: An Update on Pathophysiology, Diagnosis, and Treatment
Atypical hemolytic uremic syndrome (aHUS), a rare variant of thrombotic microangiopathy, is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment.
R. Raina +6 more
semanticscholar +1 more source
Complement factor h-antibody-associated hemolytic uremic syndrome: pathogenesis, clinical presentation, and treatment. [PDF]
The presence of circulating autoantibodies, primarily to complement factor H antibodies (CFH-Abs) in plasma characterizes the autoimmune form of atypical hemolytic uremic syndrome (aHUS).
Giner, T., Hofer, J., Józsi, Mihály
core +1 more source
Should eculizumab be discontinued in patients with atypical hemolytic uremic syndrome? [PDF]
Eva Rodríguez +2 more
openalex +1 more source
Eculizumab in the Treatment of Acetylcysteine-Induced Atypical Hemolytic Uremic Syndrome [PDF]
Arielle Jalbert +3 more
openalex +1 more source
Atypical hemolytic uremic syndrome (aHUS) is a clinical diagnosis characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. Postoperative aHUS in nontransplant patients is a rare entity.
Anil Khetarpal +2 more
doaj +1 more source
Atypical hemolytic-uremic syndrome, manifesting without thrombocytopenia (clinical case)
Background. Atypical hemolytic uremic syndrome is an ultra-rare (orphan) disease from the group of thrombotic microangiopathies of progressive course, which is caused by uncontrolled activation of the alternative complement pathway of hereditary or ...
A.A. Dyachkova +3 more
doaj +1 more source
First-line therapy in atypical hemolytic uremic syndrome: consideration on infants with a poor prognosis. [PDF]
BackgroundAtypical hemolytic uremic syndrome (aHUS) is a rare and heterogeneous disorder. The first line treatment of aHUS is plasma therapy, but in the past few years, the recommendations have changed greatly with the advent of eculizumab, a humanized ...
A Szilagyi +39 more
core +1 more source
Managing atypical hemolytic uremic syndrome: chapter 2 [PDF]
Licht et al. present the 2-year follow-up data of the landmark trials studying the efficacy of eculizumab in the treatment of atypical hemolytic uremic syndrome (aHUS). They report sustained improvements in hematologic parameters, continued safety, and additional improvements in kidney function with extended treatment.
openaire +2 more sources

