Results 81 to 90 of about 12,655 (217)

The genetics of atypical hemolytic uremic syndrome [PDF]

Medizinische Genetik, 2018
Abstract Atypical hemolytic uremic syndrome (aHUS) is a disorder characterized by thrombocytopenia and microangiopathic hemolytic anemia due to endothelial injury. aHUS is felt to be caused by defective complement regulation due to underlying genetic mutations in complement regulators or activators, most often of the alternative pathway.
Feitz, W.JC., van de Kar, N.CA.J., Orth-Höller, D., van den Heuvel, L.PJ.W., Licht, C.   +4 more
openaire   +3 more sources

Molecular Characterization of Virulent Genes and Antimicrobial Resistance Patterns of Escherichia coli Isolated From Calf Scours in Western Iran

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This study in Western Iran analysed E. coli in diarrhoeic neonatal calves and identified 307 isolates from 350 faecal samples. The pathotypes included EHEC (36.59%), EPEC (20.42%), ETEC (14.46%), STEC (12.34%) and NTEC (11.48%), with four STEC O157:H7 isolates. Serotypes O103 and O15 were the most common.
Elham Ahmadi, Mohammad Sadegh Safaee Firouzabadi, Seyed Ali Mousavi Rad, Samira Ghorbani   +3 more
wiley   +1 more source

Probiotic Development Strategy Centered on Stability and Regulatory Considerations

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT The development of probiotic strains has become a major focus in both academic and industrial research, driven by their health benefits and growing consumer demand. However, functional outcomes demonstrated under laboratory conditions often fail to align with the stability and large‐scale performance required for industrial applications ...
Hye Kim, Md Ariful Haque, Md Abdur Razzak, Min Ji Jang, Sehyeon Song, Seockmo Ku   +5 more
wiley   +1 more source

Delayed‐Onset Hemolysis in a Case of Hemolytic Uremic Syndrome: A Diagnostic Challenge

Case Reports in Hematology, Volume 2026, Issue 1, 2026.
Background Hemolytic uremic syndrome is a rare thrombotic microangiopathy characterized by hemolytic anemia, thrombocytopenia, and acute kidney injury. While commonly reported in children, adult‐onset presentations are less frequent and often atypical, leading to diagnostic delays.
Muhammad Younas, Noor Fatima, Zimal Naveed, Syeda Nafisa, Ana Antun   +4 more
wiley   +1 more source

Gemcitabine‐Induced Thrombotic Microangiopathy in Patient With Homozygous Deletion in CFHR1‐CFHR3

Case Reports in Oncological Medicine, Volume 2026, Issue 1, 2026.
We present here the case of a 66‐year‐old female with a history of pancreatic adenocarcinoma who was on a chemotherapeutic regimen of nanoparticle albumin‐bound paclitaxel (nab‐paclitaxel) and gemcitabine after demonstrating local progression of her disease on the regimen of 5‐fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX).
Natasha Dziarnowski, Morgan Puglisi, Bohdan Baralo, Hetal Vachhani, Jose I. Mayordomo   +4 more
wiley   +1 more source

Evaluating the Real‐World Safety of Ravulizumab in Generalized Myasthenia Gravis: Insights From a Detailed Analysis of FAERS Data

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
Background Ravulizumab represents the inaugural long‐acting complement C5 inhibitor that has received approval in various countries around the globe for individuals diagnosed with generalized myasthenia gravis (gMG) who are positive for anti‐acetylcholine receptor antibodies.
Yakun Wang, Qian Guo, Jiayu Bai, Jiaqi Shi, Ziquan Yang, Hongda Liu   +5 more
wiley   +1 more source

Nicotinamide Attenuates Complement and Coagulation Pathways and Resultant Renal Fibrosis

The FASEB Journal, Volume 39, Issue 23, 15 December 2025.
The coagulation and complement cascades were elevated in the pathogenesis of chronic kidney disease (CKD) and may contribute to both kidney injury and cardiovascular risk. These excessive signals and the associated innate immune responses were suppressed by the NAD+ precursor nicotinamide (NAM).
Saori Kin, Yuji Oe, Taku Obara, Emiko Sato, Nobuyuki Takahashi, Mariko Miyazaki, Tetsuhiro Tanaka   +6 more
wiley   +1 more source

Clinical case of thrombotic microangiopathy in obstetric practice

Сеченовский вестник, 2017
Trombotic microangiopathy is heterogeneous group of the diseases united by a community of a histological and clinical implications at difference of pathogenetic mechanisms, presents clinical-morphological syndrome characterizing a lesion of vessels of a ...
M. N. Mochalova, T. E. Belokrinitskaya, T. V. Haven, E. M. Shifman, K. G. Shapovalov, S. V. Kostromitin   +5 more
doaj  

A Case of Carfilzomib-Induced Atypical Hemolytic Uremic Syndrome

Annals of Internal Medicine: Clinical Cases
Atypical hemolytic uremic syndrome (aHUS) is a rare non-Shiga toxin thrombotic microangiopathy caused by uncontrolled activation of the alternative complement pathway.
Kwasi Opare-Addo, Sammudeen Ibrahim, Basilio Addo, Jorge Chancay Rodriguez   +3 more
doaj   +1 more source

ATYPICAL HEMOLYTIC-UREMIC SYNDROME IN THE FEMALE PATIENT WITH CONCURRENT MENOMETRORRHAGIA (clinical case)

Вестник анестезиологии и реаниматологии, 2018
The article describes the follow-up over the development of atypical hemolytic-uremic syndrome in the female patient suffering menometrorrhagia which manifested with concurrent metrorrhagia and was accompanied with acute renal failure.
A. V. Pyregov, T. A. Fedorova, A. Yu. Korolev, K. I. Grischuk   +3 more
doaj   +1 more source