Results 21 to 30 of about 13,218 (187)

First delirium episode in Parkinson’s disease and parkinsonism: incidence, predictors, and outcomes

npj Parkinson's Disease, 2021
To define the incidence, predictors and prognosis of the first hospital delirium episode in Parkinson’s disease (PD) and atypical parkinsonism (AP), we identified the first hospital episode of delirium after diagnosis in the Parkinsonism Incidence in ...
Samantha Green, Sarah L. Perrott, Andrew McCleary, Isobel Sleeman, Jodi Maple-Grødem, Carl E. Counsell, Angus D. Macleod   +6 more
doaj   +1 more source

Parkinsonian Syndromes in Motor Neuron Disease: A Clinical Study

Frontiers in Aging Neuroscience, 2022
BackgroundParkinsonian syndromes may rarely occur in motor neuron disease (MND). However, previous studies are heterogeneous and mostly case reports or small case series.
Jacopo Pasquini, Jacopo Pasquini, Jacopo Pasquini, Francesca Trogu, Francesca Trogu, Claudia Morelli, Barbara Poletti, Floriano Girotti, Silvia Peverelli, Alberto Brusati, Alberto Brusati, Antonia Ratti, Antonia Ratti, Andrea Ciammola, Vincenzo Silani, Vincenzo Silani, Nicola Ticozzi, Nicola Ticozzi   +17 more
doaj   +1 more source

Early Freezing of Gait: Atypical versus Typical Parkinson Disorders

Parkinson's Disease, 2015
In 18 months, 850 patients were referred to Muhammad Ali Parkinson Center (MAPC). Among them, 810 patients had typical Parkinson disease (PD) and 212 had PD for ≤5 years. Among the 212 patients with early PD, 27 (12.7%) had freezing of gait (FOG).
Abraham Lieberman, Aman Deep, Rohit Dhall, An Tran, Ming-Jai Liu   +4 more
doaj   +1 more source

Multi-modal rehabilitation therapy in Parkinson's disease and related disorders

Annals of Indian Academy of Neurology, 2023
Long-term use of dopaminergic therapy in Parkinson's disease (PD) is associated with reduction in efficacy and disabling dyskinesias. The current medical or surgical treatment modalities are ineffective for atypical parkinsonism syndromes.
Alvee Saluja, Vinay Goyal, Rajinder K Dhamija   +2 more
doaj   +1 more source

Clinical Variability of SYNJ1-Associated Early-Onset Parkinsonism

Frontiers in Neurology, 2021
Autosomal recessive early-onset parkinsonism is clinically and genetically heterogeneous. Mutations of three genes, PRKN, PINK1, and DJ-1 cause pure phenotypes usually characterized by levodopa-responsive Parkinson's disease.
Suzanne Lesage, Graziella Mangone, Christelle Tesson, Hélène Bertrand, Mustapha Benmahdjoub, Selma Kesraoui, Mohamed Arezki, Andrew Singleton, Jean-Christophe Corvol, Alexis Brice   +9 more
doaj   +1 more source

PLA2G6 Mutations Related to Distinct Phenotypes: A New Case with Early-onset Parkinsonism

Tremor and Other Hyperkinetic Movements, 2016
Background: PLA2G6-associated neurodegeneration (PLAN) is a recessive neurodegenerative disorder characterized by three distinct phenotypes: infantile neuroaxonal dystrophy (INAD), atypical neuroaxonal dystrophy (atypical NAD), and PLA2G6-related ...
Anamika Giri, Gamze Guven, Hasmet Hanagasi, Ann-Kathrin Hauser, Nihan Erginul-Unaltuna, Basar Bilgic, Hakan Gurvit, Peter Heutink, Thomas Gasser, Ebba Lohmann, Javier Simón-Sánchez   +10 more
doaj   +1 more source

Atypical parkinsonian syndromes in French Guiana: Similarities and differences with Caribbean variants

Journal of Parkinson’s Disease
Background Atypical parkinsonian syndromes are highly prevalent in the French West Indies (FWI), making up 70% of degenerative parkinsonisms and including “Caribbean Atypical Parkinsonism”. Environmental neurotoxins from Annonaceae plants are implicated.
Amina Nasri, Hugo Chaumont, Souraya Arnaud, Benoit Tressieres, Mamadou Sow, Angéla Lackmy, Régine Edragas, Mathieu Nacher, Bertrand de Toffol, Emmanuel Roze, Annie Lannuzel   +10 more
doaj   +1 more source

Effectiveness of an Inpatient Movement Disorders Program for Patients with Atypical Parkinsonism

Parkinson's Disease, 2012
This paper investigated the effectiveness of an inpatient movement disorders program for patients with atypical parkinsonism, who typically respond poorly to pharmacologic intervention and are challenging to rehabilitate as outpatients.
Anna D. Hohler, Jyeming M. Tsao, Douglas I. Katz, T. Joy DiPiero, Christina L. Hehl, Alissa Leonard, Valerie Allen, Maura Gardner, Heidi Phenix, Marie Saint-Hilaire, Terry Ellis   +10 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source