Results 21 to 30 of about 13,368 (153)

Atypical Ubiquitination and Parkinson’s Disease

International Journal of Molecular Sciences, 2022
Ubiquitination (the covalent attachment of ubiquitin molecules to target proteins) is one of the main post-translational modifications of proteins. Historically, the type of polyubiquitination, which involves K48 lysine residues of the monomeric ubiquitin, was the first studied type of ubiquitination.
Buneeva, Olga, Medvedev, Alexei
openaire   +2 more sources

Medio-Lateral Balance Impairment Differentiates between Parkinson's Disease and Atypical Parkinsonism

Journal of Parkinson’s Disease, 2014
In early disease stages, it can be difficult to differentiate clinically between Parkinson's disease and the various forms of atypical parkinsonism, like multiple system atrophy or progressive supranuclear palsy.
Jorik Nonnekes, Marjolein B. Aerts, W.F. Abdo, Bastiaan R. Bloem   +3 more
doaj   +1 more source

Corticobasal syndrome in a man with Gaucher disease type 1: Expansion of the understanding of the neurological spectrum

Molecular Genetics and Metabolism Reports, 2018
Gaucher disease (GD) is an autosomal recessive condition that results from a deficiency of the enzyme β-glucocerebrosidase. The increased risk of primary parkinsonism symptoms among individuals affected with GD and carriers for the disorder is well ...
Kunal C. Potnis, Lauren B. Flueckinger, Stephanie M. DeArmey, Roy N. Alcalay, Jeffrey W. Cooney, Priya S. Kishnani   +5 more
doaj   +1 more source

Pain in neurodegenerative diseases with atypical parkinsonism: a systematic review on prevalence, clinical presentation, and findings from experimental studies

Journal of Integrative Neuroscience, 2021
Parkinson’s disease-related pain has increasingly been investigated in research studies. Still, only a few studies have addressed the prevalence and clinical characteristics of pain in neurodegenerative disorders with atypical parkinsonism.
Jerry Yi Chang, Katarina Rukavina, Timothy Lawn, K Ray Chaudhuri   +3 more
doaj   +1 more source

Nocturnal manifestations of Parkinson’s disease and atypical Parkinsonism [PDF]

Journal of Neural Transmission, 2014
In this Supplement of the Journal of Neural Transmission, we address an important feature of Parkinson’s syndrome, i.e. nocturnal problems. We feel very honoured that so many eminent experts in this field have contributed to a supplement which should be of interest to everyone who deals with Parkinson’s disease (PD).
Heinz, Reichmann, Roongroj, Bhidayasiri
openaire   +2 more sources

Plasma Metabolite Markers of Parkinson’s Disease and Atypical Parkinsonism [PDF]

Metabolites, 2021
Differentiating between Parkinson’s disease (PD) and the atypical Parkinsonian disorders of multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) is difficult clinically due to overlapping symptomatology, especially at early disease stages.
Pathan M, Wu J, Lakso HÅ, Forsgren L, Öhman A   +4 more
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Ankylosing Spondylitis: A Risk Factor for Parkinsonism—A Nationwide Population-Based Study

Journal of Parkinson’s Disease, 2022
Background: Ankylosing spondylitis (AS) is an immune-mediated, chronic inflammatory rheumatic disorder. The etiology of Parkinson’s disease (PD) is multifactorial; however, inflammation is receiving an increasing amount of attention as an underlying ...
Seo Yeon Yoon, Seok-Jae Heo, Yong Wook Kim, Seung Nam Yang, Hyun Im Moon   +4 more
doaj   +1 more source

Parkinsonian Syndromes in Motor Neuron Disease: A Clinical Study

Frontiers in Aging Neuroscience, 2022
BackgroundParkinsonian syndromes may rarely occur in motor neuron disease (MND). However, previous studies are heterogeneous and mostly case reports or small case series.
Jacopo Pasquini, Jacopo Pasquini, Jacopo Pasquini, Francesca Trogu, Francesca Trogu, Claudia Morelli, Barbara Poletti, Floriano Girotti, Silvia Peverelli, Alberto Brusati, Alberto Brusati, Antonia Ratti, Antonia Ratti, Andrea Ciammola, Vincenzo Silani, Vincenzo Silani, Nicola Ticozzi, Nicola Ticozzi   +17 more
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Atypical parkinsonism

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2008
The dopamine deficiency syndrome Parkinson's disease (PD) is characterized by tremor, rigidity, bradykinesia and reduced postural reflexes. Conditions with similar symptoms but other causes than PD (about 1/3 of cases) are called atypical parkinsonism.
Mark Edwards, Niall Quinn, Kailash Bhatia   +2 more
openaire   +3 more sources

First delirium episode in Parkinson’s disease and parkinsonism: incidence, predictors, and outcomes

npj Parkinson's Disease, 2021
To define the incidence, predictors and prognosis of the first hospital delirium episode in Parkinson’s disease (PD) and atypical parkinsonism (AP), we identified the first hospital episode of delirium after diagnosis in the Parkinsonism Incidence in ...
Samantha Green, Sarah L. Perrott, Andrew McCleary, Isobel Sleeman, Jodi Maple-Grødem, Carl E. Counsell, Angus D. Macleod   +6 more
doaj   +1 more source