Results 51 to 60 of about 4,562,102 (274)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
PharmaceuticsGastrin-releasing peptide receptor (GRPR)-antagonists have served as motifs in the development of theranostic radioligands for prostate cancer. Our efforts have been focused on the development of radiolabeled RM26 (H-DPhe6–Gln7–Trp8–Ala9–Val10–Gly11 ...
Karim Obeid +7 more
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iScience, 2020 Summary: Biomimetic catalysts have drawn broad research interest owing to both high specificity and excellent catalytic activity. Herein, we report a series of biomimetic catalysts by the integration of biomolecules (hemin or ferrous phthalocyanine) onto
Longlong Fan +7 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Orientation Selection of Supported Au Nanoparticles on (111)- and (001)-Terminated SrTiO3 Substrates
Crystals, 2022 Orientation-dependent performance has been demonstrated in different materials consisting of nanoparticles on substrates. The fabrication of desirably oriented nanoparticles requires knowledge of orientation selection rules.
Wangwang Kuang, Guozhen Zhu
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
NanomaterialsDicyanovinyl (DCV)-substituted oligothiophenes consist of both electron donor and acceptor ligands, which makes them promising materials for organic electronics. Here, we studied the structural and electronic properties of methyl-substituted dicyanovinyl-
Lixia Kang +5 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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СТМ-дослідження впорядкування молекул діарилетенів на поверхні Аu(111)
Хімія, фізика та технологія поверхні, 2014 З використанням скануючої тунельної мікроскопії (СТМ) досліджено процес самовпорядкування терфенілтіазол-похідних діарилетенів на поверхні Au(111).
S. V. Snegir +3 more
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