Results 121 to 130 of about 228,187 (396)
Oxidative stress in the pathogenesis of systemic scleroderma: An overview [PDF]
, 2018 Systemic sclerosis (SSc) is a rare disorder of the connective tissue characterized by fibrosis of the skin, skeletal muscles and visceral organs. Additional manifestations include activation of the immune system and vascular injury. SSc causes disability
Gambardella, Lucrezia +5 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Systemic sclerosis (SSc) is a connective tissue disease with fibrotic remodeling of the skin and various internal organs. SSc is associated with the highest case‐specific mortality of all rheumatic autoimmune diseases with limited antifibrotic treatment options.
Thuong Trinh‐Minh +12 more
wiley +1 more source
Profound Thrombocytopenia and Dyspnea 11 Days After Cardiac Surgery
American Journal of Hematology, EarlyView.
Sebastian Vuong +3 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Rheumatoid arthritis (RA)–associated anticitrullinated protein antibodies (ACPAs) target various antigens by binding short citrulline amino acid motifs, resulting in heterogeneous ACPA profiles among patients. Here we analyzed ACPA patterns by recognized citrulline motifs in relation to the RA risk factors HLA‐DRB1 shared epitope (SE) alleles
Linda Mathsson Alm +18 more
wiley +1 more source
Acta Dermato-Venereologica, 2018 Anti-transcriptional intermediary factor-1γ (TIF-1γ) autoantibody may be associated with cancer in adult patients with dermatomyositis. The aim of this study was to evaluate the risk of cancer in the presence of anti-TIF-1γ autoantibody in adult ...
Marion Best +5 more
doaj +1 more source
Tropomyosin autoantibodies associated with checkpoint inhibitor myositis
OncoImmunology, 2020 This brief report details the measurement and identification of IgA antibodies to tropomyosin in a case of presumed ocular myositis with paraspinal myositis in a patient with metastatic uveal melanoma treated with checkpoint inhibitors.
Pauline Zaenker +2 more
doaj +1 more source
Diagnostics, 2020 Biomarkers are not available for monitoring the onset and progression of coronary artery disease (CAD) in patients with obstructive sleep apnea (OSA), a major risk factor for arteriosclerotic cardiovascular diseases.
Yusuke Katsumata +15 more
doaj +1 more source
Flexible Bayesian additive joint models with an application to type 1 diabetes research [PDF]
arXiv, 2016 The joint modeling of longitudinal and time-to-event data is an important tool of growing popularity to gain insights into the association between a biomarker and an event process. We develop a general framework of flexible additive joint models that allows the specification of a variety of effects, such as smooth nonlinear, time-varying and random ...
arxiv
Autoantibody-Targeted Treatments for Acute Exacerbations of Idiopathic Pulmonary Fibrosis
PLoS ONE, 2015 Background Severe acute exacerbations (AE) of idiopathic pulmonary fibrosis (IPF) are medically untreatable and often fatal within days. Recent evidence suggests autoantibodies may be involved in IPF progression.
M. Donahoe +8 more
semanticscholar +1 more source
Nuclear matrix protein 2 antibody-positive adult dermatomyositis: a case report and review of the literature [PDF]
, 2020 Dermatomyositis is a clinically heterogenous inflammatory myopathy with unique cutaneous features. Myositis-specific antibodies can aid in diagnosis and anticipation of patient prognosis.
Cartron, Alexander M +3 more
core