Results 81 to 90 of about 219,094 (347)

Capturing what matters: Patient‐reported LGI1‐ANTibody encephalitis outcome RatiNg scale (LANTERN)

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Background LGI1‐antibody encephalitis (LGI1‐Ab‐E) is a common form of autoimmune encephalitis where most patients demonstrate ‘good’ clinician‐rated outcomes. However, more targeted questionnaires reveal numerous debilitating symptoms for many years.
Mark J Kelly, Barbara Wagner, Bryan Ceronie, Christine Strippel, Ann Yee Lin, Adam Handel, John Soltys, Sophie Binks, Philip A Powell, Sarosh R Irani   +9 more
wiley   +1 more source

Type 1 diabetes recurrence after SARS‐CoV‐2 infection in a subject with pancreas transplantation

Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
During COVID‐19 pandemic, several studies have demonstrated a strong link between SARS‐CoV2 infection and diabetes mellitus. Little is known about the effects of SARS‐CoV‐2 infection on glycaemic control in pancreas transplant patients. Abstract Background During COVID‐19 pandemic, several studies have demonstrated a strong link between SARS‐CoV‐2 ...
Valentina Popolla, Alessandro Rizzi, Linda Tartaglione, Alfredo Pontecorvi, Dario Pitocco   +4 more
wiley   +1 more source

Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes [PDF]

, 2019
OBJECTIVE: Abnormally elevated proinsulin secretion has been reported in type 2 and early type 1 diabetes when significant C-peptide is present. We questioned whether individuals with long-standing type 1 diabetes and low or absent C-peptide secretory
Arvan, Peter, Bahnson, Henry T., Blum, Janice, Considine, Robert V., Davis, Asa K., DiMeglio, Linda A., Evans-Molina, Carmella, Greenbaum, Carla J., Haataja, Leena, Marcovina, Santica, Mastracci, Teresa L., Mirmira, Raghavendra G., Morris, Margaret A., Nadler, Jerry, Nyalwidhe, Julius, Qian, Wei-Jun, Schmidt, C. Max, Sims, Emily K., Speake, Cate, Swensen, Adam C., T1D Exchange Residual C-peptide Study Group, Yi, Lian, Yip-Schneider, Michele   +22 more
core   +1 more source

Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof‐of‐Concept Trial of Metformin

Arthritis & Rheumatology, 2015
Neutrophil extracellular traps (NETs) have been shown to play an important role in systemic lupus erythematosus (SLE) pathogenesis by activating plasmacytoid dendritic cells (PDCs) and the type I interferon (IFN) pathway.
Haiting Wang, Ting Li, Sheng Chen, Yue‐ying Gu, S. Ye   +4 more
semanticscholar   +1 more source

High‐Throughput Immunoassays for Cavin‐4 IgG: A Diagnostic Tool for Immune‐Mediated Rippling Muscle Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACTCavin‐4 was identified as a potential autoantigen for immune‐mediated rippling muscle disease (iRMD). To validate this, we developed and tested various immunoassays, including a cell‐based assay (CBA), cavin‐4 recombinant protein ELISA, and multi‐peptide ELISA. Among 19 iRMD patients, all exhibited muscle rippling, and 13 had percussion‐induced
Reghann G. LaFrance‐Corey, Haidara Kherbek, Nimalan Harinesan, Margherita Milone, Naveen K. Paramasivan, Pallab Sarker, Andrew M. Knight, Carley Karsten, Surendra Dasari, Teerin Liewluck, William J. Litchy, Sean J. Pittock, John R. Mills, Divyanshu Dubey   +13 more
wiley   +1 more source

Case report: Amnestic mild cognitive impairment in multiple domains associated with neurofascin 186 autoantibodies: Case series with follow-up and review

Frontiers in Psychiatry, 2023
BackgroundNeurofascin 186 autoantibodies are known to occur with a diseased peripheral nervous system. Recently, also additional central nervous system (CNS) involvement has been reported in conjunction with neurofascin 186 autoantibodies.
Niels Hansen, Niels Hansen, Anne Sagebiel, Kristin Rentzsch, Sina Hirschel, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Björn H. Schott, Björn H. Schott, Björn H. Schott, Bartels Claudia   +11 more
doaj   +1 more source

Evidence for somatic selection of natural autoantibodies. [PDF]

, 1992
Natural autoantibodies are primarily immunoglobulin M (IgM) antibodies that bind to a variety of self-antigens, including self-IgG. Accounting for a large proportion of the early B cell repertoire, such polyspecific autoantibodies are speculated to ...
Carson, DA, Duffy, SF, Kipps, TJ, Martin, T   +3 more
core  

Autoantibody-producing plasmablasts after B cell depletion identified in muscle-specific kinase myasthenia gravis.

JCI Insight, 2017
Myasthenia gravis (MG) is a B cell-mediated autoimmune disorder of neuromuscular transmission. Pathogenic autoantibodies to muscle-specific tyrosine kinase (MuSK) can be found in patients with MG who do not have detectable antibodies to the acetylcholine
P. Stathopoulos, Aditya Kumar, R. Nowak, K. O’Connor   +3 more
semanticscholar   +1 more source

Epitope Mapping of Anti‐Neurofascin 155 Antibody in a Large Cohort of Autoimmune Nodopathy Patients

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune nodopathy (AN), a newly recognized disease entity, is an immune‐mediated polyneuropathy involving autoantibodies against cell adhesion molecules located in nodes of Ranvier and paranodal regions, such as neurofascin 186 (NF186) and neurofascin 155 (NF155). The present study aimed to identify the epitopes for autoantibodies
Amina A. Abdelhadi, Hidenori Ogata, Xu Zhang, Takumi Tashiro, Ryo Yamasaki, Jun‐ichi Kira, Noriko Isobe   +6 more
wiley   +1 more source

The interference of anti-TSH autoantibody on clinical TSH detection

Frontiers in Endocrinology
ObjectiveIt is well known that macro-thyroid-stimulating hormone (macro-TSH) could interfere with the detection of TSH. The anti-TSH autoantibody is an essential component of macro-TSH.
Mulin Tang, Xue Meng, Jiajia Ni, Xue Liu, Xinhui Wang, Yuchen Li, Yuwei Chai, Chunjia Kou, Li Zhang, Haiqing Zhang, Haiqing Zhang, Haiqing Zhang, Haiqing Zhang   +12 more
doaj   +1 more source