Results 91 to 100 of about 33,778 (258)
Frontiers in ImmunologyIntroductionRheumatoid arthritis (RA) is an autoimmune disease resulting from a response driven by self-reactive CD4+ T cells that recognize autoantigenic peptides presented by antigen-presenting cells (APCs).
Diego Catalán +20 more
doaj +1 more source
Genetics and Omics Analysis of Autoimmune Skin Blistering Diseases
Frontiers in Immunology, 2019 Autoimmune blistering diseases (AIBDs) of the skin are characterized by autoantibodies against different intra-/extracellular structures within the epidermis and at the basement membrane zone (BMZ). Binding of the antibodies to their target antigen leads
Michael Olbrich +8 more
doaj +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and objectives Oral lichen planus (OLP) is a chronic autoimmune mucosal disease with malignant potential and limited treatment options. This study evaluated the long‐term efficacy and safety of cold atmospheric plasma (CAP) therapy in therapy‐refractory OLP and introduced the novel Lichen Planus Severity Score (LPSS).
Christian Seebauer +5 more
wiley +1 more source
Differentially expressed genes related to immune tolerance to diabetogenic autoantigens.
, 2013 Differentially expressed genes related to immune tolerance to diabetogenic autoantigens.
Jorge Carrascal (412907) +10 more
core +1 more source
Arquivos de Neuro-Psiquiatria, 2008 Neuromyelitis optica (NMO) is an inflammatory, demyelinating disease of the central nervous system characterized by the association of a serious myelitis and unilateral or bilateral optic neuritis.
Soniza Vieira Alves-Leon +5 more
doaj +1 more source
Hepatology Research, EarlyView.Levels of anti‐integrin αvβ6 antibodies were significantly higher in pediatric‐onset primary sclerosing cholangitis (PSC) than in autoimmune hepatitis (AIH) and may reflect disease activity. These antibodies may serve as a novel biomarker for distinguishing PSC from AIH and for monitoring disease progression.
Yukako Maeda +17 more
wiley +1 more source
Identification and functional validation of novel autoantigens in equine uveitis.
, 2006 The development, progression, and recurrence of autoimmune diseases are frequently driven by a group of participatory autoantigens. We identified and characterized novel autoantigens by analyzing the autoantibody binding pattern from horses affected by ...
Goebel, T.W. +25 more
core +1 more source
Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA
Frontiers in Immunology, 2019 The mitochondrion supplies energy to the cell and regulates apoptosis. Unlike other mammalian organelles, mitochondria are formed by binary fission and cannot be directly produced by the cell.
Yann Becker +12 more
doaj +1 more source
Tissue Resident Memory Cells: Friend or Foe?
Immunology, EarlyView.Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
Overview of autoantigens identified as potential signature profile of AIH.
, 2015 HD: healthy donors; AIH: Autoimmune hepatitis patients.^Average over 50 dataset.List of autoantigens involved in the discrimination between disease and healthy group. Using a VIP score>1 and a recognition frequency by less than 25% in HD and more than 50%
Saveria Mazzara (796365) +6 more
core +1 more source