Results 151 to 160 of about 33,778 (258)

Protective and Pathogenic Antibodies to Citrullinated Antigens

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases start years before clinical onset. In rheumatoid arthritis (RA), autoantibodies to citrullinated proteins (ACPA) and to modified IgG (rheumatoid factors, RF) can be detected many years before the inflammatory attack on cartilaginous joints. It has been assumed that these antibodies are pathogenic.
Outi Sareila, Yibo He, Zhongwei Xu, Changrong Ge, Erik Lönnblom, Rikard Holmdahl   +5 more
wiley   +1 more source

Autoantigen identification in antinuclear antibody-positive usual interstitial pneumonia without known autoantibody through immunoprecipitation-mass spectrometry. [PDF]

ERJ Open Res
Vulsteke JB, De Langhe E, De Sadeleer L, De Crem N, Yserbyt J, Dubbeldam A, Wuyts WA, Bossuyt X.   +7 more
europepmc   +1 more source

Mapping the Altered Landscape of TCR Repertoire in Autoimmune Diseases

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases arise from the breakdown of immune tolerance through complex interactions between genetic predisposition, environmental exposures, and adaptive immune responses. High‐throughput T‐cell receptor (TCR) repertoire sequencing has transformed our ability to characterize these responses, providing unprecedented insights into ...
Celine Albalaa, Martin Pezous, David Klatzmann, Encarnita Mariotti‐Ferrandiz   +3 more
wiley   +1 more source

The cascade to pathogenicity in autoantibody-mediated CNS diseases. [PDF]

Brain
Montini F, Wing E, Herman M, Pittock SJ, Lopez Chiriboga S, Flanagan EP, Irani SR.   +6 more
europepmc   +1 more source

Activation of Anergic B Cells During Development of Autoimmunity

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT In healthy individuals, autoreactive B cells are normally silenced via central and peripheral tolerance mechanisms. In the periphery, when autoreactive B cells recognize self‐antigen via their B cell receptor (BCR) (signal 1) but do not receive T cell help (signal 2), they undergo the tolerance mechanism called anergy.
Mohammad Mansoor, Brandon K. Hilliard, Mia J. Smith   +2 more
wiley   +1 more source

SPAID: a comprehensive database for disease-specific autoantigens in autoimmune disorders. [PDF]

Adv Biotechnol (Singap)
Deng S, Wei F, Pang Y, Zhang L, Zhi S, Chen T, Zuo Z, Ren J, Xie Y, Luo X.   +9 more
europepmc   +1 more source

Autoantigens

Autoimmunity, 1995
openaire   +1 more source

Tubulointerstitial Nephritis With Uveitis (TINU) Syndrome: A Case Series and Review of Literature

Nephrology, Volume 31, Issue 9, September 2026.
ABSTRACT Tubulointerstitial nephritis with uveitis (TINU) syndrome is a rare disorder characterised by the simultaneous or sequential occurrence of acute tubulointerstitial nephritis and uveitis, in the absence of systemic disease. Its true prevalence is likely underestimated, as renal and ocular manifestations may not appear concurrently. We conducted
Weaam Ali, Nidhi Agrawal, Smeeta Sinha, Dimitrios Poulikakos, Jamil Choudhury, Constantina Chrysochou   +5 more
wiley   +1 more source

Elevated Serum Soluble CD163 Indicates Macrophage Activation: A Potential Biomarker for Inflammation in Complex Regional Pain Syndrome?

Pain Practice, Volume 26, Issue 7, September 2026.
ABSTRACT Background Several studies point towards the involvement of the immune system (especially the monocyte–macrophage system) in the pathophysiology of Complex Regional Pain Syndrome (CRPS), as shown by increased levels of the cytokines tumor necrosis factor (TNF)‐α and interleukin (IL)‐6.
Nadia Kriek, Krishna Bharwani, Maaike Dirckx, Dirk Stronks, Nicole Nagtzaam, Wim A. Dik, Frank Huygen   +6 more
wiley   +1 more source

Immunoprecipitation-mass spectrometry reveals known and novel (NatC, <i>BCS1L</i>) antinuclear antibodies in rheumatoid arthritis. [PDF]

RMD Open
De Leeuw J, Michiels B, Derua R, Vulsteke JB, Dillaerts D, Cockx M, Verschueren P, Bossuyt X.   +7 more
europepmc   +1 more source