Kinetics and coexistence of autocatalytic reaction cycles [PDF]
Scientific ReportsBiological reproduction rests ultimately on chemical autocatalysis. Autocatalytic chemical cycles are thought to have played an important role in the chemical complexification en route to life. There are two, related issues: what chemical transformations
Balázs Könnyű +3 more
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The hierarchical organization of autocatalytic reaction networks and its relevance to the origin of life. [PDF]
PLoS Computational Biology, 2022 Prior work on abiogenesis, the emergence of life from non-life, suggests that it requires chemical reaction networks that contain self-amplifying motifs, namely, autocatalytic cores.
Zhen Peng, Jeff Linderoth, David A Baum
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Mathematical Analysis of a Prototypical Autocatalytic Reaction Network [PDF]
Life, 2019 Network autocatalysis, which is autocatalysis whereby a catalyst is not directly produced in a catalytic cycle, is likely to be more common in chemistry than direct autocatalysis is.
Ekaterina V. Skorb, Sergey N. Semenov
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Protocell Dynamics: Modelling Growth and Division of Lipid Vesicles Driven by an Autocatalytic Reaction [PDF]
LifeWe study a computational model of a protocell, in which an autocatalytic reaction sustains itself inside a lipid vesicle. The autocatalytic reaction drives volume growth via osmosis. Membrane area grows due to addition of lipids from the environment. The
Japraj Taneja, Paul G. Higgs
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Multispecies autocatalytic RNA reaction networks in coacervates
Communications Chemistry, 2023 Robust localization of self-reproducing autocatalytic chemistries is a key step in the realization of heritable and evolvable chemical systems. While autocatalytic chemical reaction networks already possess attributes such as heritable self-reproduction ...
Sandeep Ameta +6 more
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Mechanistic analysis and kinetic profiling of Soai’s asymmetric autocatalysis for pyridyl and pyrimidyl substrates [PDF]
Nature CommunicationsNonlinear effects in chemical reactions, coupled with amplifying catalysis, can lead to remarkable phenomena like spontaneous symmetry breaking, central to the origin of biological homochirality. Soai’s asymmetric autocatalysis is a prototypical reaction
Patrick Möhler +4 more
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The origin of large molecules in primordial autocatalytic reaction networks. [PDF]
PLoS ONE, 2012 Large molecules such as proteins and nucleic acids are crucial for life, yet their primordial origin remains a major puzzle. The production of large molecules, as we know it today, requires good catalysts, and the only good catalysts we know that can ...
Varun Giri, Sanjay Jain
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Exploring the programmability of autocatalytic chemical reaction networks
Nature CommunicationsNetworks of chemical reactions exhibit emergent properties under out-of-equilibrium conditions. Recent advances in systems chemistry demonstrate that networks with sufficient chemical complexity can be harnessed to emulate properties important for ...
Dmitrii V. Kriukov +2 more
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Spatial structure supports diversity in prebiotic autocatalytic chemical ecosystems [PDF]
npj ComplexityAutocatalysis is thought to have played an important role in the earliest stages of the origin of life. An autocatalytic cycle (AC) is a set of reactions that results in stoichiometric increase in its constituent chemicals. When the reactions of multiple
Alex M. Plum +3 more
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Chemical Engineering Journal Advances, 2022 Modeling complex chemical reaction networks has inspired a considerable body of research and a variety of approaches to modeling nonlinear pathways are being developed.
Sarang S. Nath, John Villadsen
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