Results 71 to 80 of about 9,492,165 (393)
Assessing T cell clonal size distribution: a non-parametric approach [PDF]
Clonal structure of the human peripheral T-cell repertoire is shaped by a number of homeostatic mechanisms, including antigen presentation, cytokine and cell regulation. Its accurate tuning leads to a remarkable ability to combat pathogens in all their variety, while systemic failures may lead to severe consequences like autoimmune diseases.
arxiv +1 more source
Helminth Immunomodulation in Autoimmune Disease
Helminths have evolved to become experts at subverting immune surveillance. Through potent and persistent immune tempering, helminths can remain undetected in human tissues for decades.
T. Smallwood+5 more
semanticscholar +1 more source
Electrosmog and autoimmune disease [PDF]
Studies in mice have shown that environmental electromagnetic waves tend to suppress the murine immune system with a potency similar to NSAIDs, yet the nature of any Electrosmog effects upon humans remains controversial. Previously, we reported how the human Vitamin-D receptor (VDR) and its ligand, 1,25-dihydroxyvitamin-D (1,25-D), are associated with ...
Trevor G. Marshall, Trudy J. Rumann Heil
openaire +3 more sources
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee+5 more
wiley +1 more source
Hydrolysed formula and risk of allergic or autoimmune disease: systematic review and meta-analysis
Objective To determine whether feeding infants with hydrolysed formula reduces their risk of allergic or autoimmune disease. Design Systematic review and meta-analysis, as part of a series of systematic reviews commissioned by the UK Food Standards ...
R. Boyle+12 more
semanticscholar +1 more source
Hyposalivation in autoimmune diseases [PDF]
We have investigated the prevalence of dry mouth among patients with autoimmune diseases other than Sjögren's syndrome. One hundred and forty-four patients, excluding patients with primary Sjögren's syndrome, were enrolled in this study. The volume of saliva secreted was measured with the screening technique for estimation of salivary flow, which uses ...
Hiroya Koshiba+4 more
openaire +2 more sources
The Role of Epigenetics in Autoimmune/Inflammatory Disease
Historically, systemic self-inflammatory conditions were classified as either autoinflammatory and caused by the innate immune system or autoimmune and driven by adaptive immune responses.
Anna E. A. Surace, C. Hedrich
semanticscholar +1 more source
Infectious diseases and autoimmunity
Introduction: Autoimmunity occurs when the immune system recognizes and attacks host tissue. In addition to genetic factors, environmental triggers (in particular viruses, bacteria and other infectious pathogens) are thought to play a major role in the development of autoimmune diseases.
Delogu L. G.+3 more
openaire +5 more sources
The potential roles of herpesvirus and cytomegalovirus in the exacerbation of pemphigus vulgaris
Background: Among exogenous etiologies, the critical role of microbial agents such as herpesviruses (HSV1/2) and cytomegalovirus (CMV) in triggering and flaring autoimmune conditions such as pemphigus vulgaris (PV) has been recently discovered ...
Fariba Mohammadi+11 more
doaj +1 more source
Most humans depend on sun exposure to satisfy their requirements for vitamin D. Solar ultraviolet B photons are absorbed by 7-dehydrocholesterol in the skin, leading to its transformation to previtamin D3, which is rapidly converted to vitamin D3. Season,
M. Holick
semanticscholar +1 more source