Quality of life in mild and severe alopecia areata patients
International Journal of Women's Dermatology, 2018 Background: Alopecia areata is a relapsing hair disorder characterized by a sudden hairloss and has a considerable impact on patient’s quality of life. The goal of this study was to determine quality of life among patients with mild and severe forms of ...
Robabeh Abedini +5 more
doaj +1 more source
MIRACLE: Multi-task Learning based Interpretable Regulation of Autoimmune Diseases through Common Latent Epigenetics [PDF]
arXiv, 2023 DNA methylation is a crucial regulator of gene transcription and has been linked to various diseases, including autoimmune diseases and cancers. However, diagnostics based on DNA methylation face challenges due to large feature sets and small sample sizes, resulting in overfitting and suboptimal performance. To address these issues, we propose MIRACLE,
arxiv
Autoimmune Disease-Associated Hypertension
Current Hypertension Reports, 2019 Purpose of ReviewTo highlight important new findings on the topic of autoimmune disease-associated hypertension.Recent FindingsAutoimmune diseases including systemic lupus erythematosus and rheumatoid arthritis are associated with an increased risk for ...
V. Wolf, M. Ryan
semanticscholar +1 more source
The great pretender : Autoimmune Pancreatitis [PDF]
, 2014 Autoimmune pancreatitis is a benign disorder which frequently presents with symptoms and imaging suggestive of pancreatic malignancy. Up to 21% of pancreatoduodenectomies performed for suspected pancreatic cancer are found to have benign disease ...
Azzopardi, Neville
core
Sialendoscopic management of autoimmune sialadenitis: a review of literature [PDF]
, 2017 Autoimmune diseases of major salivary glands include Sjögren's syndrome and a complex of disorders classified as immunoglobulin G4-related diseases.
DE VINCENTIIS, Marco +6 more
core +2 more sources
Eosinophils in Autoimmune Diseases [PDF]
Frontiers in Immunology, 2017 Eosinophils are multifunctional granulocytes that contribute to initiation and modulation of inflammation. Their role in asthma and parasitic infections has long been recognized. Growing evidence now reveals a role for eosinophils in autoimmune diseases.
Diny, Nicola L. +2 more
openaire +5 more sources
Autoimmune conditions and comorbid depression in pregnancy: examining the risk of preterm birth and preeclampsia. [PDF]
, 2017 ObjectiveThe objective of this study was to determine whether prenatal depression interacts with autoimmune conditions to further increase the risk of preterm birth or preeclampsia.Study designOur sample included 3034 pregnant women with rheumatoid ...
Bandoli, G, Chambers, CD
core +1 more source
Thyroid Autoantibodies Display both “Original Antigenic Sin” and Epitope Spreading
Frontiers in Immunology, 2017 Evidence for original antigenic sin in spontaneous thyroid autoimmunity is revealed by autoantibody interactions with immunodominant regions on thyroid autoantigens, thyroglobulin (Tg), thyroid peroxidase (TPO), and the thyrotropin receptor (TSHR) A ...
Sandra M. McLachlan, Basil Rapoport
doaj +1 more source
Glassy Dynamics in the Adaptive Immune Response Prevents Autoimmune Disease [PDF]
, 2005 The immune system normally protects the human host against death by infection. However, when an immune response is mistakenly directed at self antigens, autoimmune disease can occur. We describe a model of protein evolution to simulate the dynamics of the adaptive immune response to antigens.
arxiv +1 more source
graph-GPA 2.0: A Graphical Model for Multi-disease Analysis of GWAS Results with Integration of Functional Annotation Data [PDF]
arXiv, 2022 Genome-wide association studies (GWAS) have successfully identified a large number of genetic variants associated with traits and diseases. However, it still remains challenging to fully understand functional mechanisms underlying many associated variants. This is especially the case when we are interested in variants shared across multiple phenotypes.
arxiv