Results 101 to 110 of about 9,659,727 (409)
Extracellular Vesicles in Musculoskeletal Regeneration: Modulating the Therapy of the Future
Tissue regeneration is a hot topic in health sciences, particularly because effective therapies promoting the healing of several cell types are lacking, specifically those of the musculoskeletal system.
Hugo Abreu+5 more
doaj +1 more source
A Data-Efficient Deep Learning Framework for Segmentation and Classification of Histopathology Images [PDF]
The current study of cell architecture of inflammation in histopathology images commonly performed for diagnosis and research purposes excludes a lot of information available on the biopsy slide. In autoimmune diseases, major outstanding research questions remain regarding which cell types participate in inflammation at the tissue level, and how they ...
arxiv
Assessing T cell clonal size distribution: a non-parametric approach [PDF]
Clonal structure of the human peripheral T-cell repertoire is shaped by a number of homeostatic mechanisms, including antigen presentation, cytokine and cell regulation. Its accurate tuning leads to a remarkable ability to combat pathogens in all their variety, while systemic failures may lead to severe consequences like autoimmune diseases.
arxiv +1 more source
Electrosmog and autoimmune disease [PDF]
Studies in mice have shown that environmental electromagnetic waves tend to suppress the murine immune system with a potency similar to NSAIDs, yet the nature of any Electrosmog effects upon humans remains controversial. Previously, we reported how the human Vitamin-D receptor (VDR) and its ligand, 1,25-dihydroxyvitamin-D (1,25-D), are associated with ...
Trevor G. Marshall, Trudy J. Rumann Heil
openaire +3 more sources
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee+5 more
wiley +1 more source
Acute generalized exanthematous pustulosis (AGEP) is an exanthematous condition, predominantly occurring as a result of drug reactions. We, hereby, present the first case of AGEP following treatment with remdesivir in a patient with COVID-19, without ...
Fatemeh Mohaghegh+4 more
doaj +1 more source
The Autoimmune Disease Database: a dynamically compiled literature-derived database [PDF]
BACKGROUND: Autoimmune diseases are disorders caused by an immune response directed against the body's own organs, tissues and cells. In practice more than 80 clinically distinct diseases, among them systemic lupus erythematosus and rheumatoid arthritis,
Fluck, Juliane+3 more
core +3 more sources
Sarcopenia in autoimmune and rheumatic diseases: a comprehensive review [PDF]
Sarcopenia refers to a decrease in skeletal muscle mass and function. Because sarcopenia affects mortality, and causes significant disability, the clinical importance of sarcopenia is emerging.
An, Hyo Jin+14 more
core +4 more sources
Hyposalivation in autoimmune diseases [PDF]
We have investigated the prevalence of dry mouth among patients with autoimmune diseases other than Sjögren's syndrome. One hundred and forty-four patients, excluding patients with primary Sjögren's syndrome, were enrolled in this study. The volume of saliva secreted was measured with the screening technique for estimation of salivary flow, which uses ...
Hiroya Koshiba+4 more
openaire +2 more sources
HLA and non-HLA genes and familial predisposition to autoimmune diseases in families with a child affected by type 1 diabetes [PDF]
Genetic predisposition could be assumed to be causing clustering of autoimmunity in individuals and families. We tested whether HLA and non-HLA loci associate with such clustering of autoimmunity.
Finnish Pediat Diabet Register+7 more
core +8 more sources