Results 251 to 260 of about 704,631 (338)

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Clonal hematopoiesis of indeterminate potential and the risk of autoimmune diseases. [PDF]

J Intern Med
Wu H, Wei J, Yu Y, Wang N, Tan X.
europepmc   +1 more source

Circulating HLA-DR (Ia) Positive T Cells and T Cell Activation by Thyroglobulin, Thyroid Microsome, and TSH-receptor in Autoimmune Thyroid Diseases

, 1987
Kazuya Zeki, Takashi Fujihira, F Shirakawa, Kenichi Watanabe, Sumiya Eto   +4 more
openalex   +2 more sources

Gamma‐Glutamyl Cysteine Ligase Activity as a Proxy for Human T Cell Function and Drug‐Induced Immunosuppression

Advanced Science, EarlyView.
GLed, a reversible lanthanide‐based GSH sensor that enables real‐time, single‐cell measurement of Gamma–Glutamyl Cysteine Ligase (GCL) activity ‐whose role in human T cells remains unclear‐ is developed. GLed directly links GCL activity to T cell effector functions and reveals its modulation by immunosuppressive drugs, identifying GCL as a critical ...
Francisco Fueyo‐González, Carmen Salto‐Giron, Mehek Ningoo, Laura Espinar‐Barranco, Rafael Salto, Jose Manuel Paredes, Rosario Herranz, Angel Orte, Miguel Fribourg, Juan A. González‐Vera   +9 more
wiley   +1 more source

Prevalence of autoimmune diseases in patients with type 1 diabetes: a scoping review. [PDF]

Einstein (Sao Paulo)
Negrato CA, Pereira RZ, Porto LDMP, Santana YWS, Sato AKI, Melo VC, Vieira MLVE, Gomes MB.   +7 more
europepmc   +1 more source

Studies on the Production of Anti-Thyroglobulin Autoantibody in Vitro in Patients with Autoimmune Thyroid Diseases

, 1984
Yoshihito Hara
openalex   +2 more sources

METTL3/ALKBH5‐Mediated N6‐Methyladenosine Modification Drives Macrophage M1 Polarization via the SLC15A3‐TASL‐IRF5 Signaling Axis in Psoriasis

Advanced Science, EarlyView.
m6A modification stabilizes Slc15a3 mRNA in macrophages, activating the SLC15A3‐TASL‐IRF5 axis and promoting psoriatic inflammation. Abstract Impaired N6‐methyladenosine (m6A) modification has been implicated in regulating various inflammatory diseases, but its role in psoriasis remains unclear.
Tao Huang, Shijun Chen, Ke Ding, Liyan Yuan, Weiqi Lv, Kechen Chen, Yuchen Liu, Dongzhao Ma, Xin Zhang, Xiaobo Wang, Guanzheng Luo, Bin Yang, Ying Lin, Zhili Rong   +13 more
wiley   +1 more source

Fidelity of virtual self-management programs in pediatric autoimmune diseases: A scoping review protocol. [PDF]

MethodsX
Adebiyi BO, Birnie KA, Booth J, Lim LS, Rumsey D, Santana M, Stinson JN, Schmeling H.   +7 more
europepmc   +1 more source

Harnessing the Immunomodulation of UV‐Exposed Keratinocyte Extracellular Vesicles for Inflammatory Disorder Treatment

Advanced Science, EarlyView.
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu, Ding Yang, Jingsen Ji, Gengyou Li, Haoting Chen, Yuying Yao, Chenxing Fu, Fangling Liao, Jinzhao Liu, Yaming Zhang, Zechuan Li, Jing Zhang, Huike Ma, Jingxia Zhao, Ying‐Shi Sun, Weisheng Guo, Weiping Wang   +16 more
wiley   +1 more source

Editorial: Autoimmune diseases in childhood. [PDF]

Front Immunol
Liphaus BL, Demengeot J, Carneiro-Sampaio M.   +2 more
europepmc   +1 more source