Results 21 to 30 of about 472,161 (299)

Vaccinations and Autoimmune Diseases [PDF]

Vaccines, 2021
Vaccines represent one of the most effective measures of public health medicine, saving countless lives and preventing lifelong disabilities. Vaccines are extremely safe, however, no vaccine is completely free from risks and adverse events can occur following vaccination.
Bianca Olivieri, Corrado Betterle, Giovanna Zanoni   +2 more
openaire   +3 more sources

Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment

International Journal of Women's Dermatology, 2019
Frontal fibrosing alopecia (FFA) is a relatively new scarring alopecia that is considered a variant of lichen planopilaris (LPP) with no recognized promising treatments. In this study, we tried to clarify the underlying signaling pathways and their roles
Soheil Tavakolpour, PhD, HamidReza Mahmoudi, MD, Robabeh Abedini, Kambiz. Kamyab Hesari, Amin Kiani, Maryam Daneshpazhooh   +5 more
doaj   +1 more source

Autoimmune Bullous Disease Quality of Life (ABQoL) questionnaire: Validation of the translated Persian version in pemphigus vulgaris

International Journal of Women's Dermatology, 2020
Background: Autoimmune bullous diseases are a group of rare, chronic, blistering diseases, with pemphigus vulgaris (PV) being the most common type in Iran.
Amir Teimourpour, PhD, Kowsar Hedayat, MD, Fereshteh Salarvand, MD, Narges Ghandi, MD, Maryam Ghiasi, MD, Hamidreza Mahmoudi, MD, Kamran Balighi, MD, Roja Toosi, MD, MPH, Farnam Mohebi, MD, MPH, Ali Nili, MD, Maryam Daneshpazhooh, MD, Dedee F. Murrell, MA, BMBCh, MD, FACD, Cheyda Chams-Davatchi, MD   +12 more
doaj   +1 more source

Synthesis, telomerase inhibitory and anticancer activity of new 2-phenyl-4H-chromone derivatives containing 1,3,4-oxadiazole moiety

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Based on previous studies, 66 2-phenyl-4H-chromone derivatives containing amide and 1,3,4-oxadiazole moieties were prepared as potential telomerase inhibitors.
Xu Han, Yun Long Yu, Duo Ma, Zhao Yan Zhang, Xin Hua Liu   +4 more
doaj   +1 more source

Cytokine and autoantibody clusters interaction in systemic lupus erythematosus

Journal of Translational Medicine, 2017
Background Evidence supports the existence of different subphenotypes in systemic lupus erythematosus (SLE) and the pivotal role of cytokines and autoantibodies, which interact in a highly complex network.
Yovana Pacheco, Julián Barahona-Correa, Diana M. Monsalve, Yeny Acosta-Ampudia, Manuel Rojas, Yhojan Rodríguez, Juliana Saavedra, Mónica Rodríguez-Jiménez, Rubén D. Mantilla, Carolina Ramírez-Santana, Nicolás Molano-González, Juan-Manuel Anaya   +11 more
doaj   +1 more source

Thrombocytosis in a patient with acute promyelocytic leukemia during treatment with all‐trans retinoic acid and arsenic trioxide

Clinical Case Reports, 2021
Thrombocytosis is an unusual side effect of all‐trans retinoic acid (ATRA) treatment that occurs in some patients with acute promyelocytic leukemia (APL).
Maryam Habibi, Reza Manouchehri Ardekani, Hossein Motedayyen   +2 more
doaj   +1 more source

Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum

Clinical Case Reports, 2023
Key Clinical Message There is a need to pay more attention to cutaneous leishmaniasis in endemic regions which may mimic other dermatoses and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR ...
Zeinab Aryanian, Kamran Balighi, Fatameh Mohaghegh, Ifa Etesami, Zahra Razavi, Parvaneh Hatami   +5 more
doaj   +1 more source

MicroRNA in autoimmunity and autoimmune diseases

Journal of Autoimmunity, 2009
MicroRNAs (miRNAs) are small conserved non-coding RNA molecules that post-transcriptionally regulate gene expression by targeting the 3' untranslated region (UTR) of specific messenger RNAs (mRNAs) for degradation or translational repression.
Department of Oral Surgery, Diagnostic Sciences, University of Florida, Gainesville, FL, USA ( host institution ), Pauley, Kaleb M., Cha, Seunghee, Chan, Edward K.L.   +4 more
openaire   +4 more sources

Autoimmune Disease Genetics [PDF]

Clinical and Developmental Immunology, 2012
Genetic risk factors play an important role in autoimmune disease susceptibility. Recent advances genotyping techniques, statistical methods, and the organization of large patient cohorts have facilitated explosive progress in this field, and our understanding of the genetic architecture of human autoimmunity is rapidly expanding.
Mohammed Tikly, Timothy B. Niewold, Shervin Assassi, George N. Goulielmos   +3 more
openaire   +3 more sources

Hydroxychloroquine in patients with systemic lupus erythematosus: how much is enough?

Lupus Science and Medicine
Objective To assess the daily and weight-adjusted dosages of hydroxychloroquine (HCQ) and the effects on long-term remission in the Lupus-Cruces cohort.Methods Observational study of routine clinical care data. We selected inception patients treated with
Guillermo Ruiz-Irastorza, Daniel Martín-Iglesias, Ioana Ruiz-Arruza, Fernando Arizpe, Victor Moreno-Torres, Diana Paredes-Ruiz, Valerio Campos-Rodriguez, Laura Amo   +7 more
doaj   +1 more source