Results 21 to 30 of about 9,611,247 (349)

Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis

Annals of the Rheumatic Diseases, 2020
Objectives The prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases who are frequently treated with disease modifying therapies remains poorly understood. This meta-analysis aims to assess the prevalence and clinical outcomes
Shintaro Akiyama, Shadi Hamdeh, D. Micic, A. Sakuraba   +3 more
semanticscholar   +1 more source

NLRP3 Inflammasome: Checkpoint Connecting Innate and Adaptive Immunity in Autoimmune Diseases

Frontiers in Immunology, 2021
Autoimmune diseases are a broad spectrum of human diseases that are characterized by the breakdown of immune tolerance and the production of autoantibodies.
Yiwen Zhang, Wenlin Yang, Wangen Li, Yunjuan Zhao   +3 more
semanticscholar   +1 more source

NK Cells in Autoimmune Diseases: Protective or Pathogenic?

Frontiers in Immunology, 2021
Autoimmune diseases generally result from the loss of self-tolerance (i.e., failure of the immune system to distinguish self from non-self), and are characterized by autoantibody production and hyperactivation of T cells, which leads to damage of ...
Meifang Liu, S. Liang, Cai Zhang
semanticscholar   +1 more source

Autoimmunity and Otolaryngology Diseases [PDF]

Journal of Immunology Research, 2018
Many systemic autoimmune diseases have otolaryngology manifestations that could represent a diagnostic challenge for clinicians, as they often constitute an early sign of an otherwise asymptomatic autoimmune condition and may lead to delayed diagnosis and treatment.
Massimo Ralli, Arianna Di Stadio, Armando De Virgilio, Adelchi Croce, Marco de Vincentiis   +4 more
openaire   +6 more sources

Family impact of pemphigus disease in an Iranian population using the Family Dermatology Life Quality Index

International Journal of Women's Dermatology, 2020
Background: Pemphigus vulgaris (PV) is a rare but seriously disabling disorder of the skin and mucous membranes that can gravely impact the quality of life (QoL) of patients.
S. Zahra Ghodsi, MD, Arefeh Asadi, MD, Narges Ghandi, MD, Kamran Balighi, MD, Hamidreza Mahmoudi, MD, Robabeh Abedini, MD, Maryam Ghiasi, MD, Vahideh Lajevardi, MD, Cheyda Chams-Davatchi, MD, Maryam Daneshpazhooh, MD   +9 more
doaj   +1 more source

Immunogenicity and safety of the BBIBP‐CorV vaccine in patients with autoimmune inflammatory rheumatic diseases undergoing immunosuppressive therapy in a monocentric cohort

Immunity, Inflammation and Disease, 2023
Introduction Vaccination plays a fundamental role in mastering the COVID‐19 pandemic and protecting vulnerable groups. Persons with autoimmune inflammatory rheumatic diseases (AIIRD) requiring immunosuppressive therapies are prioritized for vaccination ...
Batool Zamani, Amin Moradi Hasan‐Abad, Ahmad Piroozmand, Mahsa Dehghani, Maryam Arfaatabar, Hossein Motedayyen   +5 more
doaj   +1 more source

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.

Journal of Immunology, 1995
Approximately 10% of peripheral CD4+ cells and less than 1% of CD8+ cells in normal unimmunized adult mice express the IL-2 receptor alpha-chain (CD25) molecules.
S. Sakaguchi, N. Sakaguchi, M. Asano, M. Itoh, M. Toda   +4 more
semanticscholar   +1 more source

Combination therapy for management of pemphigus patients with unexpected therapeutic response to rituximab: A report of five cases

Clinical Case Reports, 2023
Key Clinical Message The immunosuppressant agents should be considered earlier in the course of treatment with rituximab, possibly after the unfavorable response at first cycle of treatment, especially in male patients and those with high BMI.
Zeinab Aryanian, Insha Zainab Riyaz, Kamran Balighi, Ali Ahmadzade, Hamid Reza Mahmoudi, Arghavan Azizpour, Parvaneh Hatami   +6 more
doaj   +1 more source

Clinical Characteristics and Treatment Outcomes of Scleromyxedema: A 10-Year Retrospective Survey

Case Reports in Dermatology, 2022
Scleromyxedema is a rare but important mucinosis disorder of the skin that is presented with dermatological manifestations such as waxy papules, diffuse induration, and nondermatologic involvements like neurological and renal disorders.
Abtin Ansari, Zohre Erfani, Maryam Daneshpazhooh, Leila Mahmoudi, Zahra Saffarian, Kambiz Kamyab, Hamidreza Mahmoudi   +6 more
doaj   +1 more source

Autoimmune Diseases Are Linked to Type IIb Autoimmune Chronic Spontaneous Urticaria

Allergy Asthma and Immunology Research, 2021
Purpose Patients with chronic spontaneous urticaria (CSU) have an increased risk for comorbid autoimmune diseases. In this retrospective multicenter study of CSU patients, we evaluated clinical and laboratory features of CSU associated with a higher risk
P. Kolkhir, S. Altrichter, R. Asero, A. Daschner, M. Ferrer, A. Giménez-Arnau, T. Hawro, T. Jakob, T. Kinaciyan, A. Kromminga, G. Konstantinou, M. Makris, M. Metz, P. Skov, P. Staubach, G. Sussman, Ke-jun Zhang, M. Maurer   +17 more
semanticscholar   +1 more source