Results 21 to 30 of about 9,659,727 (409)

Effects of pregnancy on neuromyelitis optica spectrum disorder and predictors of related attacks

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1918-1925, December 2022., 2022
Abstract Objective Our study aimed to investigate the influence of pregnancy on the course of neuromyelitis optica spectrum disorders (NMOSD) and to explore the independent predictors of pregnancy‐related attacks. Methods We performed a retrospective study of patients with NMOSD based on the Wingerchuk 2006 or the revised Wingerchuk 2015 criteria ...
Qin Du, Ziyan Shi, Hongxi Chen, Ying Zhang, Yuhan Qiu, Yanlin Lang, Lingyao Kong, Hongyu Zhou   +7 more
wiley   +1 more source

Immune manifestations with checkpoint inhibitors in a single Brazilian center: experience and literature review

Future Science OA, 2021
Objectives: The presence of autoimmune events were recorded in patients receiving immune checkpoint inhibitors. Materials & Methods: Retrospective study in patients receiving immune checkpoint inhibitors (ICIs) during the period of 2012–2019.
Rafael A Schmerling, Antonio C Buzaid, Carolina K Haddad, Fabio AB Schutz, Fabio R Kater, Juliana Pimenta, Fernando Maluf, William N William, Camila Lopes, Dafne R Bromberg, Ana C Oliveira, Ricardo Golmia, Morton Scheinberg   +12 more
doaj   +1 more source

Emerging views of mitophagy in immunity and autoimmune diseases

Autophagy, 2020
Mitophagy is a vital form of autophagy for selective removal of dysfunctional or redundant mitochondria. Accumulating evidence implicates elimination of dysfunctional mitochondria as a powerful means employed by autophagy to keep the immune system in ...
Ye Xu, Jun Shen, Z. Ran
semanticscholar   +1 more source

COVID‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1953-1961, December 2022., 2022
Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID‐19 may cause various neurologic symptoms, including cognitive impairment.
Hanyu Zhang, Zengyuan Zhou
wiley   +1 more source

Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis

Annals of the Rheumatic Diseases, 2020
Objectives The prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases who are frequently treated with disease modifying therapies remains poorly understood. This meta-analysis aims to assess the prevalence and clinical outcomes
Shintaro Akiyama, Shadi Hamdeh, D. Micic, A. Sakuraba   +3 more
semanticscholar   +1 more source

NLRP3 Inflammasome: Checkpoint Connecting Innate and Adaptive Immunity in Autoimmune Diseases

Frontiers in Immunology, 2021
Autoimmune diseases are a broad spectrum of human diseases that are characterized by the breakdown of immune tolerance and the production of autoantibodies.
Yiwen Zhang, Wenlin Yang, Wangen Li, Yunjuan Zhao   +3 more
semanticscholar   +1 more source

Brain magnetic resonance imaging predictors in anti‐N‐methyl‐D‐aspartate receptor encephalitis

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1974-1984, December 2022., 2022
Abstract Objective Brain magnetic resonance imaging (MRI) findings in anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis are nonspecific and rarely have obvious associations with clinical characteristics and outcomes. This study aimed to comprehensively describe the MRI features of patients with NMDAR encephalitis, examine their associations with ...
Ying‐Ying Zhao, Bing Han, Cui‐Hong Qin, Xue‐Xiu Shi, Wen‐Jing Yun, Meng Wang, Bo Yuan, Tong‐Wen Sun, Hai‐Xu Wang   +8 more
wiley   +1 more source

Stigma Experience in Patients With Vitiligo: A Comprehensive Study in a Skin Hospital

Acta Medica Iranica, 2022
Vitiligo is the most common cause of skin depigmentation, which relates to a wide range of psychological disorders. Stigma is defined as a negative attitude towards oneself that results from one's perception of being different from the general ...
Ali Zare Dehnavi, Maryam Daneshpazhooh, Abbas Dehghani, Kamran Balighi, Arghavan Azizpour, Mehdi Yaseri, Seyed Mohammad Seyed Ebrahimi, Hamidreza Mahmoudi   +7 more
doaj   +1 more source

NK Cells in Autoimmune Diseases: Protective or Pathogenic?

Frontiers in Immunology, 2021
Autoimmune diseases generally result from the loss of self-tolerance (i.e., failure of the immune system to distinguish self from non-self), and are characterized by autoantibody production and hyperactivation of T cells, which leads to damage of ...
Meifang Liu, S. Liang, Cai Zhang
semanticscholar   +1 more source

Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation [PDF]

, 2014
Autoimmune diseases are driven by immune cells that recognize self-tissues. A major goal for treatment strategies for autoimmune diseases is to turn off or tolerize self-reactive immune cells such as CD4 T cells that coordinate tissue damage in many ...
A. David, Ahmed, Araki, Bauer, Black, Bour-Jordan, Chappert, Crawford, Endres, F. Crawford, Ferraro, Getts, Hasselberg, Higgins, Huster, J. W. Kappler, Kearney, Leech, London, Lumsden, M. MacLeod, Macleod, McAleer, McKinstry, Ndejembi, Nepom, O'neill, Okkenhaug, P. Garside, P. Marrack, Prakken, Raychaudhuri, Sabatos-Peyton, Song, Valujskikh, Verbeek, Walsh, Wilkinson, Zhai   +38 more
core   +1 more source