Results 31 to 40 of about 9,706,967 (334)

Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis

open access: yesAnnals of the Rheumatic Diseases, 2020
Objectives The prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases who are frequently treated with disease modifying therapies remains poorly understood. This meta-analysis aims to assess the prevalence and clinical outcomes
Shintaro Akiyama   +3 more
semanticscholar   +1 more source

NLRP3 Inflammasome: Checkpoint Connecting Innate and Adaptive Immunity in Autoimmune Diseases

open access: yesFrontiers in Immunology, 2021
Autoimmune diseases are a broad spectrum of human diseases that are characterized by the breakdown of immune tolerance and the production of autoantibodies.
Yiwen Zhang   +3 more
semanticscholar   +1 more source

Stigma Experience in Patients With Vitiligo: A Comprehensive Study in a Skin Hospital

open access: yesActa Medica Iranica, 2022
Vitiligo is the most common cause of skin depigmentation, which relates to a wide range of psychological disorders. Stigma is defined as a negative attitude towards oneself that results from one's perception of being different from the general ...
Ali Zare Dehnavi   +7 more
doaj   +1 more source

Association of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA) [PDF]

open access: yes, 2012
The cytokine IL-10 and its family members have been implicated in autoimmune diseases and we have previously reported that genetic variants in IL-10 were associated with a rare group of diseases called juvenile idiopathic arthritis (JIA). The aim of this
Bryant, A   +12 more
core   +17 more sources

Epstein-Barr Virus and Systemic Autoimmune Diseases

open access: yesFrontiers in Immunology, 2021
Epstein-Barr Virus (EBV) is an extremely successful human herpes virus, which infects essentially all human beings at some time during their life span. EBV infection and the associated immune response results in production of antibodies (seroconversion),
G. Houen, N. Trier
semanticscholar   +1 more source

NK Cells in Autoimmune Diseases: Protective or Pathogenic?

open access: yesFrontiers in Immunology, 2021
Autoimmune diseases generally result from the loss of self-tolerance (i.e., failure of the immune system to distinguish self from non-self), and are characterized by autoantibody production and hyperactivation of T cells, which leads to damage of ...
Meifang Liu, S. Liang, Cai Zhang
semanticscholar   +1 more source

Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation [PDF]

open access: yes, 2014
Autoimmune diseases are driven by immune cells that recognize self-tissues. A major goal for treatment strategies for autoimmune diseases is to turn off or tolerize self-reactive immune cells such as CD4 T cells that coordinate tissue damage in many ...
A. David   +38 more
core   +1 more source

Sialendoscopic management of autoimmune sialadenitis: a review of literature [PDF]

open access: yes, 2017
Autoimmune diseases of major salivary glands include Sjögren's syndrome and a complex of disorders classified as immunoglobulin G4-related diseases.
DE VINCENTIIS, Marco   +6 more
core   +2 more sources

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.

open access: yesJournal of Immunology, 1995
Approximately 10% of peripheral CD4+ cells and less than 1% of CD8+ cells in normal unimmunized adult mice express the IL-2 receptor alpha-chain (CD25) molecules.
S. Sakaguchi   +4 more
semanticscholar   +1 more source

Immunogenicity and safety of the BBIBP‐CorV vaccine in patients with autoimmune inflammatory rheumatic diseases undergoing immunosuppressive therapy in a monocentric cohort

open access: yesImmunity, Inflammation and Disease, 2023
Introduction Vaccination plays a fundamental role in mastering the COVID‐19 pandemic and protecting vulnerable groups. Persons with autoimmune inflammatory rheumatic diseases (AIIRD) requiring immunosuppressive therapies are prioritized for vaccination ...
Batool Zamani   +5 more
doaj   +1 more source

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