Results 31 to 40 of about 153,226 (196)

Pathogenesis of autoimmune demyelination: from multiple sclerosis to neuromyelitis optica spectrum disorders and myelin oligodendrocyte glycoprotein antibody‐associated disease

Clinical & Translational Immunology, 2021
Autoimmunity plays a significant role in the pathogenesis of demyelination. Multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) are now recognised as ...
Joseph A Lopez, Martina Denkova, Sudarshini Ramanathan, Russell C Dale, Fabienne Brilot   +4 more
doaj   +1 more source

Autoimmunity: The nuclear arsenal of autoimmunity [PDF]

Immunology & Cell Biology, 2007
An exciting new work recently published in Nature Immunology shows that an iconic molecule should not get all the blame for carrying out the dirty work of autoimmunity ...
openaire   +3 more sources

Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation

Genome Biology, 2020
We present Mustache, a new method for multi-scale detection of chromatin loops from Hi-C and Micro-C contact maps. Mustache employs scale-space theory, a technical advance in computer vision, to detect blob-shaped objects in contact maps.
Abbas Roayaei Ardakany, Halil Tuvan Gezer, Stefano Lonardi, Ferhat Ay   +3 more
doaj   +1 more source

Application of High-Throughput Imaging Mass Cytometry Hyperion in Cancer Research

Frontiers in Immunology, 2022
Imaging mass cytometry (IMC) enables the in situ analysis of in-depth-phenotyped cells in their native microenvironment within the preserved architecture of a single tissue section.
Marion Le Rochais, Marion Le Rochais, Patrice Hemon, Jacques-Olivier Pers, Arnaud Uguen, Arnaud Uguen   +5 more
doaj   +1 more source

Apheresis in Autoimmune Encephalitis and Autoimmune Dementia [PDF]

Journal of Clinical Medicine, 2020
Autoimmune encephalitis (AE) is a rapidly progressive inflammatory neurological disease. Underlying autoantibodies can bind to neuronal surfaces and synaptic proteins resulting in psychiatric symptoms, focal neurological signs, autonomic dysfunction and cognitive decline.
Harald Prüss, Harald Prüss, Rosa Rössling, Rosa Rössling   +3 more
openaire   +3 more sources

Perspective on Protein Arginine Deiminase Activity—Bicarbonate Is a pH-Independent Regulator of Citrullination

Frontiers in Immunology, 2018
Protein citrullination catalyzed by peptidyl arginine deiminase (PADs) is involved in autoimmune disease pathogenesis, especially in rheumatoid arthritis.
Yebin Zhou, Nanette Mittereder, Gary P. Sims   +2 more
doaj   +1 more source

Web Tool for Navigating and Plotting SomaLogic ADAT Files

Journal of Open Research Software, 2017
SOMAscan™ is a complex proteomic platform created by SomaLogic. Experimental data resulting from the assay is provided by SomaLogic in a proprietary text-based format called ADAT.
Foo Cheung, Giovanna Fantoni, Maria Conner, Brian A. Sellers, Yuri Kotliarov, Julián Candia, Katherine Stagliano, Angélique Biancotto   +7 more
doaj   +1 more source

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Post-COVID Syndrome: A Common Neuroimmune Ground?

Diagnostics, 2022
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease of unknown etiology, sharing a similar clinical presentation with the increasingly recognized post-COVID syndrome.
Varvara A. Ryabkova, Natalia Y. Gavrilova, Tamara V. Fedotkina, Leonid P. Churilov, Yehuda Shoenfeld   +4 more
doaj   +1 more source

Major Histocompatibility Complex Class II Deficiency Beyond Infancy

Case Reports in Immunology
Major histocompatibility complex class (MHC)-II deficiency is a rare autosomal recessive combined immunodeficiency, accounting for 4.1% of inborn errors of immunity (IEI) cases in North Africa and the Middle East.
Aziza Bachir Kattra, Ibtihal Benhsaien, Asmaa Drissi Bourhanbour, Zahra Aadam, Abderrahmane Errami, Fatima Ailal, Ahmed Aziz Bousfiha, Jalila El Bakkouri   +7 more
doaj   +1 more source

Characterization of the Hypercitrullination Reaction in Human Neutrophils and Other Leukocytes

Mediators of Inflammation, 2015
Autoantibodies against citrullinated proteins are diagnostic for rheumatoid arthritis. However, the molecular mechanisms driving protein citrullination in patients with rheumatoid arthritis remain poorly understood. Using two independent western blotting
Yebin Zhou, Tiziana Di Pucchio, Gary P. Sims, Nanette Mittereder, Tomas Mustelin   +4 more
doaj   +1 more source