Results 51 to 60 of about 339,261 (412)

Pathogenesis of autoimmune demyelination: from multiple sclerosis to neuromyelitis optica spectrum disorders and myelin oligodendrocyte glycoprotein antibody‐associated disease

open access: yesClinical & Translational Immunology, 2021
Autoimmunity plays a significant role in the pathogenesis of demyelination. Multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) are now recognised as ...
Joseph A Lopez   +4 more
doaj   +1 more source

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Post-COVID Syndrome: A Common Neuroimmune Ground?

open access: yesDiagnostics, 2022
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease of unknown etiology, sharing a similar clinical presentation with the increasingly recognized post-COVID syndrome.
Varvara A. Ryabkova   +4 more
doaj   +1 more source

A nonconservative kinetic model under the action of an external force field for modeling the medical treatment of autoimmune response [PDF]

open access: yes, 2023
In this paper, we develop a new nonconservative kinetic framework to be applied for the study of immune system dysregulation. From the modeling viewpoint, the new kinetic model regards a system, composed of stochastically interacting agents, under the action of an eternal force field.
arxiv   +1 more source

Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms

open access: yesViruses, 2019
For a long time, viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren’s syndrome (SS), herpetic stromal keratitis ...
M. Smatti   +5 more
semanticscholar   +1 more source

Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice

open access: yesScience Translational Medicine, 2020
Gut microbiota dysbiosis induces lupus-like autoimmunity in mice through altered tryptophan catabolism. The advantage of reducing dietary tryptophan Alterations in the gut microbiota may contribute to autoimmunity through bacterial-mediated immune ...
Seung-Chul Choi   +10 more
semanticscholar   +1 more source

A Toll for lupus [PDF]

open access: yes, 2005
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
Anders HJ, H-J Anders, Stacey KJ
core   +1 more source

Application of High-Throughput Imaging Mass Cytometry Hyperion in Cancer Research

open access: yesFrontiers in Immunology, 2022
Imaging mass cytometry (IMC) enables the in situ analysis of in-depth-phenotyped cells in their native microenvironment within the preserved architecture of a single tissue section.
Marion Le Rochais   +5 more
doaj   +1 more source

CD38: An Immunomodulatory Molecule in Inflammation and Autoimmunity

open access: yesFrontiers in Immunology, 2020
CD38 is a molecule that can act as an enzyme, with NAD-depleting and intracellular signaling activity, or as a receptor with adhesive functions. CD38 can be found expressed either on the cell surface, where it may face the extracellular milieu or the ...
Z. Piedra-Quintero   +3 more
semanticscholar   +1 more source

Molecular mimicry, genetic homology, and gene sharing proteomic “molecular fingerprints” using an EBV (Epstein-Barr virus)-derived microarray as a potential diagnostic method in autoimmune disease [PDF]

open access: yes, 2018
EBV (Epstein-Barr Virus) and other human DNA viruses are associated with autoimmune syndromes in epidemiologic studies. In this work, immunoglobulin G response to EBV-encoded proteins which share regions with human immune response proteins from the human
Alessandra Farina, Giuseppina   +2 more
core   +1 more source

Perspective on Protein Arginine Deiminase Activity—Bicarbonate Is a pH-Independent Regulator of Citrullination

open access: yesFrontiers in Immunology, 2018
Protein citrullination catalyzed by peptidyl arginine deiminase (PADs) is involved in autoimmune disease pathogenesis, especially in rheumatoid arthritis.
Yebin Zhou   +2 more
doaj   +1 more source

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