Results 161 to 170 of about 5,157 (210)
The Antibacterial Effect of Cannabigerol toward Streptococcus mutans Is Influenced by the Autoinducers 21-CSP and AI-2 [PDF]
Biomedicines, 2023 Bacteria can communicate through an intercellular signaling system referred to as quorum sensing (QS). The QS system involves the production of autoinducers that interact with their respective receptors, leading to the induction of specific signal ...
Ronit Vogt Sionov +2 more
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The role of microbial dormancy autoinducers in metabolism blockade [PDF]
Microbiology, 2000 Alkyl-substituted hydroxybenzenes (AHBs), which are autoinducers of microbial dormancy (d1 factors), were found to stabilize the structure of protein macromolecules and modify the catalytic activity of enzymes.
Alexey Kolpakov +2 more
exaly +2 more sources
Stabilization of enzymes by dormancy autoinducers as a possible mechanism of resistance of resting microbial forms [PDF]
Microbiology, 2000 Alkyl-substituted hydroxybenzenes (AHBs), autoinducers of microbial dormancy (or d1 factors), were found to stabilize the structure of protein macromolecules, making them metabolically less active and more resistant to stresses. In vitro experiments with
Alexey Kolpakov +2 more
exaly +2 more sources
N‐Acylated Alanine Methyl Esters (NAMEs) from Roseovarius tolerans, Structural Analogs of Quorum‐Sensing Autoinducers, N‐Acylhomoserine Lactones [PDF]
Chemistry and Biodiversity, 2013 The Roseobacter clade is one of the most important bacteria group living in the ocean. Liquid cultures of Roseovarius tolerans EL 164 were investigated for the production of autoinducers such as N-acylhomoserine lactones (AHLs) and other secondary ...
Irène Wagner-Döbler +2 more
exaly +2 more sources
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Custom Synthesis of Autoinducers and Their Analogues
2010Bacterial quorum sensing (QS) system is a unique target for the development of a new class of drugs that potentially control pathogenicity and attenuate virulence. Thus, it has been of significant interest to discover small organic molecules that modulate QS circuits by competing with the signaling molecules, or so-called autoinducers (AIs), for ...
Jun, Igarashi, Hiroaki, Suga
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Autoinduced synthesis of colicin E2
Molecular and General Genetics MGG, 1983Escherichia coli K-12 cells carrying the high copy number plasmid ColE2-P9 and a sfiA-lacZ gene fusion exhibit abnormally high levels of SOS-regulated phi sfiA-lacZ expression. Increased sfiA-lacZ expression is caused by the action of colicin E2, which is a DNase, rather than by the presence of multiple copies of a binding site for LexA protein, the ...
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Novel synthetic analogs of the Pseudomonas autoinducer
Bioorganic & Medicinal Chemistry Letters, 1999Release of virulence factors in Pseudomonas aeruginosa is regulated by two N-acylhomoserine lactones, PAI-1 and PAI-2, that activate the respective transcription factors LasR and RhlR. With the goal of developing novel therapeutic agents, we synthesized constrained analogs of PAI-1 and evaluated them in P. aeruginosa.
T, Kline +5 more
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Analogs of the autoinducer of bioluminescence inVibrio fischer
Archives of Microbiology, 1986The enzymes for luminescence in Vibrio fischeri are induced only when a sufficient concentration of a metabolic product (autoinducer) specifically produced by this species accumulates. It has previously been shown that the autoinducer is 3-oxohexanoyl homoserine lactone and that it enters the cells by simple diffusion. To further study the mechanism of
A, Eberhard +3 more
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Structural identification of autoinducer of Photobacterium fischeri luciferase
Biochemistry, 1981Synthesis of bacterial luciferase in some strains of luminous bacteria requires a threshold concentration of an autoinducer synthesized by the bacteria and excreted into the medium. Autoinducer excreted by Photobacterium fischeri strain MJ-1 was isolated from the cell-free medium by extraction with ethyl acetate, evaporation of solvent, workup with ...
A, Eberhard +5 more
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Isolation of agr Quorum Sensing Autoinducers
2010Autoregulation of genes is often associated with quorum sensing systems where bacteria produce and secrete molecules that allow the cells to communicate with one another, leading to the activation of certain genes at certain population densities. Here we describe the identification of the agr as a quorum sensing system in Staphylococcus aureus and the ...
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