Results 171 to 180 of about 8,210 (215)

Biogenic Quorum-Sensing Amides from <i>Streptomyces</i> sp. NP10. [PDF]

Molecules
Genčić MS, Ilic-Tomic T, Mladenović MZ, Živković Stošić MZ, Nikodinovic-Runic J, Radulović NS.   +5 more
europepmc   +1 more source

Disclosing New Insights on Pyrazolo[3,4-<i>d</i>] Pyrimidine Tethered Diverse Amino Acid Candidates as Potential DHFR Inhibitors and Anti-Virulence Agents. [PDF]

J Microbiol Biotechnol
Ibrahim TS, Salem IM, Alhakamy NA, Al-Mahmoudy AMM, Hegazy WAH.   +4 more
europepmc   +1 more source

Harmine acts as a quorum sensing inhibitor decreasing the virulence and antibiotic resistance of Pseudomonas aeruginosa. [PDF]

BMC Infect Dis
Chen P, Qin J, Su HK, Du L, Zeng Q.
europepmc   +1 more source

Quinolones: from antibiotics to autoinducers [PDF]

FEMS Microbiology Reviews, 2011
Since quinine was first isolated, animals, plants and microorganisms producing a wide variety of quinolone compounds have been discovered, several of which possess medicinally interesting properties ranging from antiallergenic and anticancer to antimicrobial activities.
Stephan Heeb, Stephen P Diggle, Paul Williams   +2 more
exaly   +3 more sources

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Autoinduced synthesis of colicin E2

Molecular and General Genetics MGG, 1983
Escherichia coli K-12 cells carrying the high copy number plasmid ColE2-P9 and a sfiA-lacZ gene fusion exhibit abnormally high levels of SOS-regulated phi sfiA-lacZ expression. Increased sfiA-lacZ expression is caused by the action of colicin E2, which is a DNase, rather than by the presence of multiple copies of a binding site for LexA protein, the ...
openaire   +2 more sources

Novel synthetic analogs of the Pseudomonas autoinducer

Bioorganic & Medicinal Chemistry Letters, 1999
Release of virulence factors in Pseudomonas aeruginosa is regulated by two N-acylhomoserine lactones, PAI-1 and PAI-2, that activate the respective transcription factors LasR and RhlR. With the goal of developing novel therapeutic agents, we synthesized constrained analogs of PAI-1 and evaluated them in P. aeruginosa.
T, Kline, J, Bowman, B H, Iglewski, T, de Kievit, Y, Kakai, L, Passador   +5 more
openaire   +2 more sources

Autoinducing peptide-based quorum signaling systems in Clostridioides difficile

Current Opinion in Microbiology, 2022
The autoinducing peptide-based Agr system in Clostridioides difficile is involved in virulence factor expression, motility, and sporulation. This review highlights several of the recent discoveries regarding C. difficile Agr. Typical Agr systems rely on the combined activities of four proteins involved in peptide expression, peptide processing, peptide
Ummey Khalecha Bintha Ahmed, Jimmy D Ballard   +1 more
openaire   +2 more sources

Bacterial Interference Caused by Autoinducing Peptide Variants

Science, 1997
The synthesis of virulence factors and other extracellular proteins by Staphylococcus aureus is globally controlled by the agr locus, which encodes a two-component signaling pathway whose activating ligand is an agr -encoded autoinducing peptide.
G, Ji, R, Beavis, R P, Novick
openaire   +2 more sources

Peptide autoinducers in bacteria

Microbiology, 2009
The review classifies and analyzes the literature data on bacterial peptide autoinducers (AIs), responsible for intra- and interspecies communication (quorum sensing) between bacterial populations. The most important families of peptide AI are discussed, including a large group of bacteriocins, subdivided into lantibiotics (class I), unmodified heat ...
openaire   +1 more source