Results 1 to 10 of about 4,782 (111)

Autolysin Production from Chlamydomonas reinhardtii [PDF]

Bio-Protocol, 2023
Chlamydomonas reinhardtii is a model organism for various processes, from photosynthesis to cilia biogenesis, and a great chassis to learn more about biofuel production.
Justin Findinier
doaj   +2 more sources

Streptococcus suis autolysin functions as a molecular bridge for epithelial adhesion via lipoteichoic acid interaction [PDF]

Infection and Immunity
As a zoonotic opportunistic pathogen, adhesion to the porcine upper respiratory tract epithelium is a prerequisite for Streptococcus suis serotype 2 (SS2) to breach epithelial barriers and cause systemic infections under certain conditions. In this study,
Mingxing Liu, Hong Zhou, Xin Shan, Jingzhi Yuan, Kaiyue Yang, Mengzan Yang, Jinsheng Tang, Fei Pan, Huixing Lin, Zhe Ma, Hongjie Fan   +10 more
doaj   +2 more sources

Cell wall mechanical stress could coordinate septal synthesis and scission in Staphylococcus aureus [PDF]

mBio
Staphylococcus aureus divides by building a septum and then splitting into two daughter cells. Scission should be coordinated with septum completion to avoid cell lysis; however, it is not known how this is achieved, or what the relative roles of ...
Sheila Hoshyaripour, Marco Mauri, Jamie K. Hobbs, Simon J. Foster, Rosalind J. Allen   +4 more
doaj   +2 more sources

Biochemical characterization and X-ray structural and mutagenic analyses of the putative autolysin CdCwlT33800 catalytic domain from Clostridioides difficile [PDF]

Applied and Environmental Microbiology
Clostridioides difficile is a major pathogen of pseudomembranous colitis, and new antimicrobial agents are needed for its treatment. Autolysins are peptidoglycan-degrading enzymes that generally reorganize the cell wall during cell division but kill ...
Hiroshi Sekiya, Yasuhiro Nonaka, Shigehiro Kamitori, Eiji Tamai   +3 more
doaj   +2 more sources

A new regulator of the Staphylococcus aureus peptidoglycan hydrolase Sle1. [PDF]

PLoS Genetics
Regulation of peptidoglycan hydrolases is crucial for bacterial cell integrity, growth and division. In the bacterial pathogen Staphylococcus aureus, the amidase Sle1 is a key autolysin required for septum splitting and daughter cell separation.
Helena Veiga, Adrian Izquierdo-Martinez, Leonor B Marques, Mariana G Pinho   +3 more
doaj   +2 more sources

Characterization of the major autolysin (AtlC) of Staphylococcus carnosus [PDF]

BMC Microbiology
Background Autolysis by cellular peptidoglycan hydrolases (PGH) is a well-known phenomenon in bacteria. During food fermentation, autolysis of starter cultures can exert an accelerating effect, as described in many studies on cheese ripening. In contrast,
Maximilian Merz, Carolin J. Schiffer, Andreas Klingl, Matthias A. Ehrmann   +3 more
doaj   +2 more sources

Inhibiting Peptidoglycan Hydrolase Alleviates MRSA Pneumonia Through Autolysin-Mediated MDP-NOD2 Pathway [PDF]

Infection and Drug Resistance
Yang Yang,1,2 Zongze Yao,1 Jiazhen Zhang,1 Wei Shao,3 Bo Li,2 Huihui Wu,2 Wenjian Tang,3 Jing Zhang2 1School of Medicine, Anhui University of Science and Technology, Huainan, People’s Republic of China; 2Anhui Province Key Laboratory of Occupational ...
Yang Y, Yao Z, Zhang J, Shao W, Li B, Wu H, Tang W, Zhang J   +7 more
doaj   +2 more sources

Coptis rhizome extract influence on Streptococcus pneumoniae through autolysin activation [PDF]

AMB Express
This study investigated the antibacterial properties of Coptis rhizome, a plant traditionally used for respiratory infections, against Streptoccus pneumonia (S. pneumoniae), for which there has been minimal empirical evidence of effectiveness.
Eon-Bee Lee, Kyubae Lee
doaj   +2 more sources

Discovery of (phenylureido)piperidinyl benzamides as prospective inhibitors of bacterial autolysin E from Staphylococcus aureus

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Autolysin E (AtlE) is a cell wall degrading enzyme that catalyzes the hydrolysis of the β-1,4-glycosidic bond between the N-acetylglucosamine and N-acetylmuramic acid units of the bacterial peptidoglycan.
Jure Borišek, Sara Pintar, Simona Golic Grdadolnik   +2 more
exaly   +2 more sources

Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Methicillin-resistant Staphylococcus aureus (MRSA) reasons extreme infections, can resist various conventional antimicrobial agents, and cause morbidity and mortality worldwide.
Setareh Haghighat, Seyed Davar Siadat, Abbas Akhavan Sepahi, Mehdi Mahdavi   +3 more
doaj   +1 more source