Results 11 to 20 of about 4,864 (173)

Cloning of Minor Autolysin of Streptococcus Pneumoniae

open access: yesMedical Laboratory Journal, 2015
Background and Objective: Increased antibiotic resistant strains and inadequacy of current vaccines against pneumococcal infections necessitate the study of novel protein antigens.
Mahboobi, R   +5 more
doaj   +1 more source

Selenium Nanoparticles as a Co-adjuvant with Autolysin Recombinant Protein in the Development of a Vaccine Candidate Against Methicillin-Resistant Staphylococcus Aureus [PDF]

open access: yesمجله دانشکده پزشکی اصفهان, 2022
Background: Methicillin-resistant Staphylococcus aureus (MRSA) causes various infections in susceptible individuals who are resistant to antibiotics, resulting in high morbidity and mortality rates.
Alireza Ranjbariyan   +3 more
doaj   +1 more source

Demonstration of Virulence Factors in Streptococcus Pneumoniae Isolates from a Tertiary Hospital in South India [PDF]

open access: yesNational Journal of Laboratory Medicine, 2017
Introduction: Streptococcus pneumoniae (pneumococci) colonizes the nasopharynx and 94 different serotypes have been characterized on the basis of the capsular polysaccharides.
Jayashree Veerasamy   +1 more
doaj   +1 more source

Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation

open access: yesFEBS Open Bio, 2022
Recruitment of plasminogen is an important infection strategy of the human pathogen Streptococcus pneumoniae to invade host tissues. In Streptococcus aureus, triosephosphate isomerase (TPI) has been reported to bind plasminogen. In this study, the TPI of
Satoru Hirayama   +7 more
doaj   +1 more source

Design of a novel affinity probe using the cell wall-binding domain of a Listeria monocytogenes autolysin for pathogen detection

open access: yesMicrobiology Spectrum, 2023
Rapid identification of foods and food-processing environments contaminated with Listeria monocytogenes is crucial for controlling human listeriosis, a leading cause of fatality related to foodborne illnesses. The L.
Min Lin, Hanhong Dan
doaj   +1 more source

The Pneumococcal Protein SufC Binds to Host Plasminogen and Promotes Its Conversion into Plasmin

open access: yesMicroorganisms, 2023
Streptococcus pneumoniae causes otitis media, sinusitis, and serious diseases such as pneumonia and bacteremia. However, the in vivo dynamics of S. pneumoniae infections and disease severity are not fully understood.
Yoshihito Yasui   +7 more
doaj   +1 more source

Novel P335-like Phage Resistance Arises from Deletion within Putative Autolysin yccB in Lactococcus lactis

open access: yesViruses, 2023
Lactococcus lactis and Lactococcus cremoris are broadly utilized as starter cultures for fermented dairy products and are inherently impacted by bacteriophage (phage) attacks in the industrial environment.
Jenny Seiler   +4 more
doaj   +1 more source

Staphylococcus aureus Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis

open access: yesFrontiers in Microbiology, 2021
Staphylococcus aureus invasion of the osteocyte lacuno-canalicular network (OLCN) is a novel mechanism of bacterial persistence and immune evasion in chronic osteomyelitis. Previous work highlighted S.
Elysia A. Masters   +19 more
doaj   +1 more source

Contribution of autolysin to virulence of Streptococcus pneumoniae [PDF]

open access: yesInfection and Immunity, 1989
Insertion-duplication mutagenesis was used to construct an autolysin-negative derivative of Streptococcus pneumoniae. This derivative was obtained by first transforming the nonencapsulated strain Rx1 with a derivative of the vector pVA891 carrying a 375-base-pair TaqI DNA fragment from the middle of the autolysin structural gene. DNA was extracted from
A M, Berry   +3 more
openaire   +2 more sources

Building blocks and blueprints for bacterial autolysins

open access: yesPLOS Computational Biology, 2021
Bacteria utilize a wide variety of endogenous cell wall hydrolases, or autolysins, to remodel their cell walls during processes including cell division, biofilm formation, and programmed death. We here systematically investigate the composition of these enzymes in order to gain insights into their associated biological processes, potential ways to ...
Spencer J. Mitchell   +3 more
openaire   +4 more sources

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