Results 111 to 120 of about 774,197 (183)

A high-yield automated radiosynthesis of the alpha-7nicotinic receptor radioligand[18F]NS10743

[18F]NS10743, a promising and highly competitive α7 nAChR radioligand has been synthesized so far by microwave irradiation using a manual single-mode device followed by a palladium-catalyzed reduction of remaining nitro-precursor for HPLC separation ...
大西 新, 須原 哲也, Oh-Nishi, Arata, Teodoro, Rodrigo, 469879, 469878, Brust, Peter, 469877, 469876, Wenzel, Barbara, Fischer, Steffen, Deuther-Conrad, Winnie, 469885, 469884, Suhara, Tetsuya, 469883, 469882, 469881, 469880, Peters, Dan   +19 more
core  

Improved two-step radiosynthesis of [¹⁸F]T807(1).

, 2019
Improved two-step radiosynthesis of [18F]T807(1).
Ling-Wei Hsin (1912123), Chyng-Yann Shiue (823852), Chia-Ling Tsai (3111771), Ming-Jang Chiu (173124), Kuo-Hsing Ma (616060), Ya-Yao Huang (3111768), Chi-Han Wu (6900368), Ruoh-Fang Yen (778232), Hao-Yu Hsieh (6900362), Cheng-Yi Cheng (796895), Ching-Hung Chiu (6900365), Kai-Yuan Tzen (436050)   +11 more
core   +1 more source

Cyclotron production of short-lived radionuclides and labelled compounds for use in biomedical research and clinical diagnosis [PDF]

, 1994
The works submitted in this thesis cover the development of methods for the production in a cyclotron of a variety of radionuclides and their incorporation in radio-labelled compounds for use in biomedical research. In addition, papers are included which
Clark, John Charles
core  

Phenothiazine structures and radiosynthesis of [¹²⁵I]SIL23.

, 2013
Structures of SIL23 analogues are shown in A. The radiosynthesis of [125I]SIL23 is shown in B.
Zhude Tu (279779), Paul T. Kotzbauer (241155), Lihai Yu (279776), Joel S. Perlmutter (279777), Jinbin Xu (33400), Robert H. Mach (279778), Devika P. Bagchi (279775)   +6 more
core   +1 more source

Radiosynthesis of [¹¹C]ITMM with conventional or ultra-high SA.

, 2015
Radiosynthesis of [11C]ITMM with conventional or ultra-high SA.
Masanao Ogawa (136804), Kazunori Kawamura (136818), Ming-Rong Zhang (136828), Hidekatsu Wakizaka (416889), Akiko Hatori (136785), Masayuki Fujinaga (136798), Joji Yui (136787), Nobuki Nengaki (136810), Tomoyuki Ohya (755248), Lin Xie (136792), Tomoteru Yamasaki (136789), Yoko Ikoma (755249)   +11 more
core   +1 more source

The automated radiosynthesis and purification of the opioid receptor antagonist, [6- O -methyl- 11 C]diprenorphine on the GE TRACERlab FX FE radiochemistry module

, 2014
[6-O-Methyl-(11)C]diprenorphine ([(11)C]diprenorphine) is a positron emission tomography ligand used to probe the endogenous opioid system in vivo. Diprenorphine acts as an antagonist at all of the opioid receptor subtypes, that is, μ (mu), κ (kappa) and
Anthony Jones, Fairclough, Michael, Brown, Gavin, Prenant, Christian, Adam McMahon, Jonathan Lowe, Jones, AKP, Lowe, Jonathan, Mcmahon, Adam; id_orcid, Jones, Anthony, Michael Fairclough, Christian Prenant, Gavin Brown   +12 more
core   +1 more source

Radiosynthesis of [2-11C-carbonyl]dantrolene using [11C]phosgene for PET

Automated radiosynthesis of [2-11C-carbonyl]dantrolene, the substrate of breast cancer resistance protein (BCRP/ABCG2), was performed for the first time through a multi-step/one-pot labeling sequence that started with ethyl 2-{2-[5-(4-nitrophenyl ...
478475, 478474, 福村 利光, 478477, 478476, 478471, 478470, Suzuki, Hisashi, 478473, 478472, 鈴木 寿, 高田 由貴, Takada, Yuuki, 小川 政直, Fukumura, Toshimitsu, Ogawa, Masanao   +15 more
core  

Step-by-step optimisation of the radiosynthesis of the brain HDAC6 radioligand [18F]FSW-100 for clinical applications

EJNMMI Radiopharmacy and Chemistry
Background Histone deacetylase 6 (HDAC6) is an emerging target for the treatment and diagnosis of proteinopathies. [18F]FSW-100 was recently developed as a promising brain-penetrating radioligand for HDAC6 PET imaging and the process validation of [18F ...
Tetsuro Tago, Jun Toyohara
doaj   +1 more source

Automated radiosynthesis and in vivo evaluation of ¹⁸F-labeled analog of the photosensitizer ADPM06 for planning photodynamic therapy. [PDF]

EJNMMI Radiopharm Chem, 2023
Kawamura K, Yamasaki T, Fujinaga M, Kokufuta T, Zhang Y, Mori W, Kurihara Y, Ogawa M, Tsukagoe K, Nengaki N, Zhang MR.   +10 more
europepmc   +1 more source

Optimization of Automated Radiosynthesis of Gallium-68-Labeled PSMA11 with Two [⁶⁸Ge]Ge/[⁶⁸Ga]Ga Generators: Fractional Elution or Prepurification? [PDF]

Pharmaceuticals (Basel), 2023
Durieux F, Dekyndt B, Legrand JF, Rogeau A, Malek E, Semah F, Odou P.   +6 more
europepmc   +1 more source