Results 61 to 70 of about 1,184,702 (285)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Advanced Data Classification Framework for Enhancing Cyber Security in Autonomous Vehicles
AutomationAutonomous vehicles (AVs) have revolutionized the automotive industry by leveraging data to perceive and interact with their environment effectively.
Shiva Ram Neupane, Weiqing Sun
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Automatic Electrical Appliances Control Panel Based on Infrared and Wi-Fi: A Framework for Electrical Energy Conservation [PDF]
, 2011 -Today, proprietary home automation targets very specific applications which operate mostly on a cable based infrastructure. In contrast to that, our implementation builds on a wireless platform for the automatic control of house hold electrical ...
Adetiba, E. +4 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Asian Roboticism: Connecting Mechanized Labor to the Automation of Work [PDF]
, 2020 This article reconsiders the present-day automation of work and its transformation of who we are as humans. What has been missing from this important conversation are the social meanings surrounding Asian roboticism or how Asians have already been ...
Bui, Long
core +1 more source
The Responsibility Quantification (ResQu) Model of Human Interaction with Automation
, 2020 Intelligent systems and advanced automation are involved in information collection and evaluation, in decision-making and in the implementation of chosen actions. In such systems, human responsibility becomes equivocal.
Douer, Nir, Meyer, Joachim
core +1 more source
AutomationEfficient irrigation water use directly affects crop productivity as demand increases for various agricultural products due to population growth worldwide.
Munir Oudah +4 more
doaj +1 more source