Results 61 to 70 of about 6,762 (312)

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Research on the Decision-Making and Control System Architecture for Autonomous Berthing of MASS

Journal of Marine Science and Engineering
Autonomous berthing is a critical phase in the fully autonomous navigation process of MASS (Maritime Autonomous Surface Ship). However, the autonomous berthing stage of MASS is significantly influenced by environmental factors and involves a wide range ...
Haoze Zhang, Yingjun Zhang, Hongrui Lu, Yihan Niu   +3 more
doaj   +1 more source

Cyber-Risk Assessment for Autonomous Ships [PDF]

2018 International Conference on Cyber Security and Protection of Digital Services (Cyber Security), 2018
As a $183.3 Billion industry controlling 90 % of all world trade, the shipping community is continuously looking for methods to increase profits while still considering human and environmental safety. As a result of developing technologies and policy that make autonomy a feasible solution, at least three separate organizations are aiming to produce and
Kimberly Tam, Kevin D. Jones
openaire   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Development of a Numerical Simulation Model to Support the Design of a Ship–Satellite Communication System for Autonomous Marine Navigation [PDF]

, 2023
Federico Del Mondo, Stefano Seriani, Paolo Gallina, A. Gregorio, Rodolfo Taccani   +4 more
openalex   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays

Advanced Science, EarlyView.
An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen, Bin Li, Yingying Wang, Fulin Zhu, Wenxuan Yang, Xuanyu Fu, Tiantian Man, Qiuyue Wu, Kewei Ren, Shengyuan Deng   +9 more
wiley   +1 more source

In Situ Polyurea Integration for Self‐Healing, Durable Transparent Electromagnetic‐Interference Shielding Film

Advanced Science, EarlyView.
A steric‐hindrance molecular engineering strategy uses dimethyl maleate (DMM) to convert poly(1,4‐butanediol) bis(4‐aminobenzoate) (PBDAB) into a precursor with reduced reactivity via Michael addition, thereby retarding the curing process to form a transparent, ultraflexible, and self‐healable secondary‑amine polyurea (PuSA) with a crosslinked network.
Sinan Zheng, Shanyu Zhao, Gengjiang Yao, Yue Liu, Fei Pan, Mingrui Han, Zecheng Li, Shanbo Li, Jiurong Liu, Na Wu, Zhihui Zeng   +10 more
wiley   +1 more source

Ship Autonomous Berthing Strategy Based on Improved Linear-Quadratic Regulator

Journal of Marine Science and Engineering
There has been significant interest in the research field of ship automatic navigation, particularly in the area of autonomous berthing. To address the key challenges of path planning and control during ship berthing, we propose an enhanced Linear ...
Jian Yin, Guoquan Chen, Shenhua Yang, Zeyang Huang, Yongfeng Suo   +4 more
doaj   +1 more source