Results 71 to 80 of about 860,212 (248)

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

open access: yesAdvanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin   +18 more
wiley   +1 more source

Dynamic game collision avoidance decision-making for autonomous and manned ships

open access: yesZhongguo Jianchuan Yanjiu
ObjectiveThis study investigates the interactive collision avoidance (CA) problem of autonomous and manned ships in mixed navigation scenarios in order to achieve the efficient collision avoidance and safe navigation of ships.
Hao CUI   +4 more
doaj   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

open access: yesAdvanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao   +10 more
wiley   +1 more source

A two-stage littoral warfare ship system design [PDF]

open access: yes, 1995
Part of the TSSE Team 1994 - Littoral Warfare Mother Ship ...
Thiel, R.   +6 more
core   +1 more source

Regional Deterrence Ship

open access: yes, 1992
Web page capture of TSSE Team 1992 - Regional Deterrence Ship project page, as it appeared July ‎2, ‎2025.This ship was to be highly effective at operating in littoral waters to deter regional conflicts between third world nations and at hampering the ...

core  

Estimation of Ship-to-Ship Link Persistence in Maritime Autonomous Surface Ship Communication Scenarios

open access: yes
Maritime Autonomous Surface Ships (MASSs) are expected to become vital participants in future maritime commerce and ocean development activities. This paper investigates a channel capacity-based scheme for estimating the persistence of ship-to-ship ...
Xiaoyu Du, Shuaiheng Huai, Qing Hu
core   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

open access: yesAdvanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran   +10 more
wiley   +1 more source

Towards approval of autonomous ship systems by their operational envelope. [PDF]

open access: yesJ Mar Sci Technol, 2022
Rødseth ØJ   +2 more
europepmc   +1 more source

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang   +8 more
wiley   +1 more source

Efficient collaborative collision avoidance algorithm considering COLREGs in complex multi-ship encounter scenarios

open access: yesApplied Ocean Research
In recent years, the issue of autonomous ship collision avoidance has attracted widespread attention. Although various automatic collision avoidance algorithms have been proposed, the development of decision-making systems for collision avoidance in ...
Zhanshuo Zhang   +3 more
doaj   +1 more source

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