Results 61 to 70 of about 7,478,685 (249)

Benefits of teaching styles and student-centred methodologies in Physical Education

open access: yesE-balonmano.com: Revista de Ciencias del Deporte, 2018
The competence-based approach in education required a modification of the teaching performance, promoting the use of active and student-centred methodologies. The didactics of Physical Education has a previous theoretical framework that conceptualizes on
Jorge Agustín Zapatero Ayuso
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Understanding maternal support for autonomy in young children with Down Syndrome [PDF]

open access: yes, 2016
Prior research has highlighted the importance of supporting the autonomy of children with Down syndrome from early childhood. There is some evidence to suggest that mothers of children with Down syndrome are more directive than those whose children are ...
Susana Gavidia‐Payne   +7 more
core   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Fiscal autonomy for Scotland? A rejoinder [PDF]

open access: yes, 2006
In their paper „A restatement of the case for fiscal autonomy‟ Hallwood and MacDonald (2006b) claim that Barnett is a formula for a rake‟s progress and that fiscal autonomy, as outlined in their previous paper „The economic case for Scottish fiscal ...
Swales, John K.   +2 more
core   +2 more sources

Estilos motivacionais de professores: propriedades psicométricas de um instrumento de avaliação

open access: yesPsicologia: Teoria e Pesquisa
O objetivo deste estudo foi submeter à análise fatorial exploratória um instrumento de avaliação de estilos motivacionais de professores, elaborado por Deci e colaboradores, denominado Problems in School.
Sueli Édi Rufini Guimarães   +2 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Bidirectional Relationship between Positive Parenting Behavior and Children’s Self-Regulation: A Three-Wave Longitudinal Study

open access: yesBehavioral Sciences
In this study, we used a cross-lagged design to explore the relationship between children’s self-regulation and positive parenting behaviors. Children aged 3 years (N = 84) were tested individually three times a year for their hot and cool self ...
Su Wang, Xiaosong Gai
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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