Results 211 to 220 of about 72,795 (291)

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

The E193K LRRK2 mutation interferes with the autophagosome processing through the impairment of the LRRK2-Dynein-1 complex. [PDF]

Sci Rep
Redl S, Zweydorf FV, Gloeckner CJ, Posadas I, Ceña V, Hess MW, Piccoli G, Pérez-Carrión MD.   +7 more
europepmc   +1 more source

Comparative Transcriptomic Analysis of Human Macrophages During Mycobacterium avium Versus Mycobacterium tuberculosis Infection

Molecular Microbiology, EarlyView.
Human macrophage transcriptomic responses to Mycobacterium avium (Mav), a major cause of nontuberculous lung disease, were compared to Mycobacterium tuberculosis (Mtb). Both infections activated overlapping immune pathways, including cytokine signaling and GPCRs involved in lipid metabolism, while phospholipases were more strongly regulated by Mav and ...
Gül Kilinç, Robin H. G. A. van den Biggelaar, Tom H. M. Ottenhoff, Leon H. Mei, Anno Saris   +4 more
wiley   +1 more source

Plant rhabdovirus glycoprotein activates unfolded protein response-mediated antiviral ER-phagy in insect vectors. [PDF]

PLoS Pathog
Chen S, Cheng Y, Tang Y, Zhang J, Li Y, Jia D, Chen H, Wei T.   +7 more
europepmc   +1 more source

Defender or accomplice? Dual roles of plant vesicle trafficking in restricting and enabling geminiviral systemic infection

New Phytologist, EarlyView.
Summary The vesicle trafficking system enables multidirectional cargo fluxes between endomembrane compartments. However, vesicle trafficking plays dual roles during pathogen infections. In plants, it mediates autophagic immune responses but can also be hijacked by pathogens to facilitate successful infections.
Pepe Cana‐Quijada, Pablo Morales‐Martínez, Tábata Rosas‐Díaz, Jessica Pérez‐Sancho, Tamara Jiménez‐Góngora, José Antonio Navarro, Rosa Lozano‐Durán, Araceli G. Castillo, Vicente Pallás, Eduardo R. Bejarano   +9 more
wiley   +1 more source

Pinellia pedatisecta Schott-Derived Exosome-Like Nanovesicles Promote Apoptosis in Colorectal Cancer by Regulating the Lysosome-Mediated Mitophagy Pathway. [PDF]

Food Sci Nutr
Zhou P, Zhang Q, Zhou X, Zhang G, Cheng S.   +4 more
europepmc   +1 more source

From recognition to response: integrated signaling pathways determining pollen acceptance and rejection in Brassicaceae

New Phytologist, EarlyView.
Summary Generation of competent offspring is vital for the prosperity of flowering plants. The pistil not only functions as a conduit for pollen tubes to grow to the ovary but also provides a selective venue for facilitating the growth of compatible pollen tubes and discouraging invaders and incompatible pollen.
Tong Zhang, Shuyan Li, Shengwei Dou, Qiaohong Duan   +3 more
wiley   +1 more source

Dangerous Membranes: Viruses That Subvert Autophagosomes

EBioMedicine, 2014
William T. Jackson
doaj   +1 more source

Lysosomal capturing of cytoplasmic injected nanoparticles by autophagy: an additional barrier to non viral gene delivery [PDF]

, 2014
Braeckmans, Kevin, De Smedt, Stefaan, Klumperman, Judith, Oorschot, Viola, Remaut, Katrien   +4 more
core   +1 more source

USP10 in Neurological Disorders: Mechanistic Insights and Emerging Therapeutic Strategies

Annals of the New York Academy of Sciences, EarlyView.
USP10 is a deubiquitinating enzyme that affects neurological diseases through multiple mechanisms, including the accumulation of toxic proteins, autophagy, and immune responses. In this review, we discuss the structure and characteristics of USP10 and summarize the role of USP10 in neurological disorders.
Celemuge, Hongying Sun, Jia Zhang, Yang Yang, Jian Mao, Cheliger   +5 more
wiley   +1 more source