Novel Mechanism of the L-Type Voltage-Gated Channels/Calpains Axis in Influenza A Virus-Induced Autophagosome Activity. [PDF]
Murphy H, Ly H.
europepmc +1 more source
The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes +6 more
wiley +1 more source
Autophagy and mitophagy at the synapse and beyond: implications for learning, memory and neurological disorders. [PDF]
Lu J +5 more
europepmc +1 more source
ABSTRACT Autophagy and the ubiquitin/26S proteasome system (UPS) play critical roles in the immune defence of the host against pathogen invasion. As a countermeasure, pathogens deploy effector proteins to subvert or hijack autophagy and UPS processes.
Yaqian Shi +7 more
wiley +1 more source
Coxsackievirus A10 blocks autophagosome-lysosome fusion to promote viral nonlytic spread and inflammatory cytokine release. [PDF]
Wang R +7 more
europepmc +1 more source
ABSTRACT The plant endomembrane system and vesicle trafficking are central to plant immunity, mediating the targeted delivery and recycling of defence molecules during pathogen attack. Here, we investigated the functional role of soybean Vacuole Membrane Protein 1 (GmVMP1) in mediating resistance against soybean cyst nematode (SCN, Heterodera glycines).
Tracy E. Hawk +15 more
wiley +1 more source
TGF-β2 increases eHSP90α secretion via upregulating secretory autophagy pathway. [PDF]
Li J +16 more
europepmc +1 more source
ABSTRACT BS39 is a broad‐based population of tropical maize adapted to temperate environments that can provide useful and unique alleles to US Corn Belt breeding programmes. Doubled‐haploid (DH) has been used as an efficient alternative method to speed up the development of maize lines. Our objectives were to compare genetic parameters for plant height
Gabriela dos Santos Pereira +6 more
wiley +1 more source
The COP9 signalosome variants CSNCSN7A and CSNCSN7B form complexes with specific CRLs which are targets of autophagy. [PDF]
Dubiel W, Dubiel D.
europepmc +1 more source
Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima +6 more
wiley +1 more source

